INBRE: CLAFLIN U: FACULTY AND UNDERGRADUATE RESEARCH DEVELOPMENT

INBRE：CLAFLIN U：教师和本科生研究发展

• 批准号: 7959586
• 负责人: Rebecca Bullard-Dillard
• 金额: $ 40.08万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-01 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7959586
• 关键词: Administrator; Area; Arts; Biomedical Engineering; Biomedical Research; Biotechnology; Cancer Center; Cells; Collaborations; Colon Carcinoma; Commit; Computer Retrieval of Information on Scientific Projects Database; DNA Sequencing Facility; Development; Faculty; Funding; Grant; Historically Black Colleges and Universities; Human Papillomavirus; Human papillomavirus 16; Institutes; Institution; Internships; Laboratory Technicians; Link; Master of Science; Mediating; Mentors; Microbial Biofilms; Minority; Molecular Target; Outcome; Phase; Pilot Projects; Positioning Attribute; Postdoctoral Fellow; Proteins; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Role; Source; South Carolina; Students; Training; Training Support; United States National Institutes of Health; Universities; Viral; Wages; Zinc; design; graduate student; medical schools; member; programs; prostate cancer prevention; research and development; success

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Claflin University is located in Orangeburg, South Carolina, only 35 miles from the University of South Carolina (USC). Claflin University is the first HBCU in the state to start a Center for Biotechnology (The South Carolina Center for Biotechnology or SCCBT) as well as instituting a new Masters of Science (MS) program in Biotechnology. As a mentored institution of the SC-BRIN, Claflin established a state-of-the-art DNA sequencing facility. Claflin University benefited greatly by inclusion in the first phase of the SC-BRIN. Our administrators (in particular our President) are committed to developing a research program for the entire institution as a direct outcome of the SC-BRIN. We have already established collaborative links between five of our faculty and faculty at USC and Clemson University through the SC-BRIN and we are ready to step-up our research enterprise, assuring that our program will contribute to the overall success of the SC-INBRE. This application focuses on three research infrastructure building areas: 1) For Student Training, we propose: a. Support for a total of 15 graduate student (MS) INBRE Research Fellows b. Support for a total of 18 academic year undergraduate research internships 2) For Faculty Development, we request support for the development of two collaborative research projects involving two new tenure track faculty hires at Claflin. Dr. Jianguo Chen (our SC-BRIN Faculty Fellow) will be developing the project A: "Viral and Host Cell Determinants of Human Papillomavirus (HPV) Type 16 Integration and HPV-mediated Transformation". Dr. Randall Harris (hired in January 04) will be developing the project B: "Role of Biofilms in the Development of Colon Cancer." Both projects will be mentored by senior faculty at the South Carolina Cancer Center. To further develop our research enterprise, we request support for a third pilot project maturing from an existing collaboration with the USC School of Medicine. Project C: "Molecular Targets for Zinc in Prostate Cancer Prevention", will be led by Dr. Omar Bagasra, a senior faculty member at Claflin. 3) For Faculty, Postdoctoral, and Staff Recruitment we are requesting: a) Salary support and start-up packages for two newly approved tenure track faculty positions, a protein biochemist and a structural biochemist; b) support and training for two minority post-doctoral researchers; and c) support for laboratory technicians for the SCCBT. Together, these three sets of activities are all designed to enhance the research programs of the SCCBT and will allow Claflin University's faculty, students, and research staff to contribute substantially to the overall South Carolina INBRE theme of Developmental and Applied Bioengineering.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 克拉夫林大学位于南卡罗来纳州的奥兰治堡，距离南卡罗来纳大学（USC）仅35英里。 克拉夫林大学是该州首位建立生物技术中心（南卡罗来纳州生物技术或SCCBT中心）的HBCU，也是建立新的科学硕士（MS）生物技术大师计划的HBCU。作为SC-BRIN的指导机构，Claflin建立了最先进的DNA测序设施。 克拉夫林大学（Claflin University）在SC-BRIN的第一阶段中受益匪浅。 我们的管理人员（尤其是我们的总统）致力于为整个机构制定研究计划，作为SC-BRIN的直接结果。 我们已经通过SC-Brin在USC和Clemson University的五个教职员工之间建立了合作联系，我们准备提高研究企业，并确保我们的计划将有助于SC-Inbre的整体成功。 该申请重点介绍三个研究基础设施建设领域： 1）对于学生培训，我们建议： 一个。支持总共15名研究生（MS）Inbre Research Fellows b。支持总共18个学年的本科生研究实习 2）对于教师发展，我们要求支持两个合作研究项目，涉及克拉夫林的两名新终身教师雇用。 Jianguo Chen博士（我们的SC-BRIN教职员工）将开发该项目：“人乳头瘤病毒（HPV）16型整合和HPV介导的转换的病毒和宿主细胞决定因素”。 兰德尔·哈里斯（Randall Harris）博士（于1月4日雇用）将开发B：“生物膜在结肠癌发展中的作用”。这两个项目将由南卡罗来纳州癌症中心的高级教师指导。为了进一步发展我们的研究企业，我们要求支持第三个试点项目，该项目与USC医学院现有合作成熟。 项目C：“预防前列腺癌中锌的分子靶标”将由克拉夫林的高级教师奥马尔·巴格斯拉（Omar Bagasra）博士领导。 3）对于教师，博士后和员工招聘，我们要求：a）两个新批准的任期教师职位，蛋白质生物化学家和一名结构生物化学家的工资支持和启动套餐； b）对两名少数民族后研究人员的支持和培训； c）支持SCCBT实验室技术人员。这三组活动共同旨在增强SCCBT的研究计划，并允许克拉夫林大学的教职员工，学生和研究人员为南卡罗来纳州整体的发展和应用生物工程的主题做出基本贡献。