SEQUENCE DETERMINANTS OF PROTEIN STRUCTURE AND FUNCTION

蛋白质结构和功能的序列决定因素

• 批准号: 7955082
• 负责人: Robert T Sauer
• 金额: $ 0.25万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7955082
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Enzymes; Funding; Grant; Institution; Proteins; Research; Research Personnel; Resources; Source; United States National Institutes of Health; protein structure function; structural biology

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Under the auspices of this project, we are studying how AAA+ enzymes including ClpXP, HslUV, and Lon catalyze ATP-dependent denaturation of specific target proteins and subsequent degradation.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 在该项目的主持下，我们正在研究AAA+酶（包括CLPXP，HSLUV和LON）的AAA+酶如何催化特定靶蛋白的ATP依赖性变性以及随后的降解。