OVARIAN HORMONE MODULATION OF ICP: MRI STUDIES

ICP 的卵巢激素调节：MRI 研究

• 批准号: 7950799
• 负责人: ANAT BIEGON
• 金额: $ 0.37万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-12-01 至 2009-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7950799
• 关键词: Age; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Intracranial Hypertension; Intracranial Pressure; Magnetic Resonance Imaging; Methods; Ovarian hormone; Premenopause; Pseudotumor Cerebri; Research; Research Personnel; Resources; Risk; Source; Time; Traumatic Brain Injury; United States National Institutes of Health; Woman; base; epidemiologic data; men; older women

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study are to study the influence of ovarian hormones on intracranial pressure (ICP) by a non invasive, MRI based method using a 3T magnet. Our hypothesis is that intracranial pressure is influenced by ovarian hormones, based on our recent findings that women under the age of 50 are at increased risk to develop intracranial hypertension following traumatic brain injury and epidemiologic data that demonstrate that idiopathic intracranial hypertension (also known as pseudotumor cerebri) is 7 times more common in premenopausal women compared with men or older women.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究的目的是通过使用 3T 磁铁的非侵入性 MRI 方法来研究卵巢激素对颅内压 (ICP) 的影响。我们的假设是，颅内压受卵巢激素的影响，基于我们最近的发现，即 50 岁以下的女性在创伤性脑损伤后发生颅内高压的风险增加，并且流行病学数据表明特发性颅内高压（也称为假性肿瘤） cerebri）在绝经前女性中的发病率是男性或老年女性的 7 倍。