PROTOCOL #191622-057

协议

• 批准号: 7951269
• 负责人: THYAGARAJAN SUBRAMANIAN
• 金额: $ 0.05万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7951269
• 关键词: Botox; Clinical Research; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Muscle Tonus; Patients; Protocols documentation; Research; Research Personnel; Resources; Respiratory Diaphragm; Respiratory physiology; Risk; Safety; Source; Stroke; United States National Institutes of Health; pulmonary function

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The objective of this study is to assess the safety of BOTOX in terms of pulmonary function in patients with reduced lung function. BOTOX is used to reduce muscle tone and has been used to treat spasticity following a stroke. There is a risk that this treatment could compromise the diaphragm and pulmonary function.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究的目的是评估肺功能降低患者肺功能的安全性。肉毒杆菌毒素用于减少肌肉张力，并已用来治疗中风后的痉挛。 这种治疗可能会损害隔膜和肺功能。