Neuroeconomics of Drug Addiction

毒瘾的神经经济学

• 批准号: 7856466
• 负责人: DAVID FITZPATRICK
• 金额: $ 65.96万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7856466
• 关键词: Academic Medical Centers; Acute; Ally; Animal Model; Area; Award; Behavioral; Behavioral Sciences; Biological; Biological Psychiatry; Biology; Brain; Brain imaging; Businesses; CCNA2 gene; Cancer Biology; Cellular biology; Cessation Research; Collaborations; Communities; Complement; Decision Making; Development; Discipline; Disease; Doctor of Philosophy; Drug Addiction; Economic Models; Economics; Educational Activities; Educational process of instructing; Educational workshop; Electrophysiology (science); Ensure; Faculty; Family; Fostering; Functional Magnetic Resonance Imaging; Functional disorder; Funding Agency; Genetic Predisposition to Disease; Genetically Modified Animals; Genome; Goals; Health Sciences; Health behavior; Ice; Incubators; Individual; Industry; Institutes; Institution; Journals; Knowledge; Laboratories; Learning; Life; Link; Marketing; Medical Psychology; Modeling; Molecular; National Institute of Drug Abuse; Neurobiology; Neurosciences; Neurosciences Research; Nicotine; Paper; Pathology; Pharmacology; Portraits; Positioning Attribute; Prevention Research; Process; Psychiatry; Psychology; Recruitment Activity; Research; Research Personnel; Research Project Grants; Resources; Role; Rosa; Schools; Science; Secure; Series; Social Psychology; Social Sciences; Societies; Sorting - Cell Movement; Students; System; Techniques; Testing; Training; Transgenic Mouse Facility; United States National Institutes of Health; Universities; Update; Ursidae Family; Work; addiction; base; brain behavior; cognitive neuroscience; design; graduate student; insight; interest; meetings; neuroeconomics; novel; novel strategies; practical application; professor; programs; ranpirnase; remediation; smoking cessation; social; tool; web site; working group

DESCRIPTION (provided by applicant): The nascent interdisciplinary field of Neuroeconomics harnesses the computational rigor of economics and the technological advances of modern biology to advance discovery in the decision sciences. Since pathologies of decision making are endemic to addiction-they serve a causal role in its development, they exacerbate the biological and social consequences of the disorder, and they impair remediation and treatment ~ the National Institutes of Health has recognized Neuroeconomics as fundamental to solving this important societal problem. Here we propose a National Institute of Drug Abuse (NIDA) P30 Core Center uniting two areas of institutional strength at Duke, Neuroeconomics/Cognitive Neuroscience and Interdisciplinary Addiction Research, to support hiring two new faculty, each in partnership with the Duke Institute for Brain Sciences (DIBS) and an academic department: Duke is an internationally recognized leader in both of these fields, yet their collective strengths have not yet been brought to bear on core problems of decision making in addiction. There are several areas of existing institutional strength in these areas that include the Center for Neuroeconomic Studies (CNS), the Center for Cognitive Neuroscience (CCN), the NIDA-supported Translational Prevention Research Center (TPRC), the Duke Center for Nicotine and Smoking Cessation Research (CNSCR), The Fuqua School of Business, and the strong behavioral neuroscience groups within the Departments of Neurobiology, Psychiatry, and Psychology and Neuroscience. Despite these strengths, fundamental gaps remain. The proposed Core Center will fill important gaps in the Duke decision-making research community, will bring important and cutting-edge research competencies, and will strengthen Duke's position as one of the leading institutions in this important research area. It will bring new teaching capabilities to the undergraduate neuroscience major and to graduate training more broadly. Finally, it will provide an important new link for DIBS to socially relevant applications for neuroscience, consistent with Duke's strategic goal of "Knowledge in the Sen/ice of Society". A NIDA P30 Core Center will give Duke the leverage to immediately fill these gaps and catalyze integration of these disparate groups by hiring two new faculties that each brings new expertise bridging current Neuroeconomics and Addiction research at Duke.

描述（由申请人提供）：新兴的跨学科领域神经经济学利用经济学的计算严谨性和现代生物学的技术进步来推进决策科学的发现。由于决策病理是成瘾的特有现象，它们在成瘾的发展中起着因果作用，它们加剧了疾病的生物和社会后果，并且损害了补救和治疗〜美国国立卫生研究院已认识到神经经济学是解决这一问题的基础重要的社会问题。在此，我们提议建立国家药物滥用研究所 (NIDA) P30 核心中心，联合杜克大学的两个机构优势领域：神经经济学/认知神经科学和跨学科成瘾研究，以支持聘用两名新教师，每名教师均与杜克大学脑科学研究所合作（DIBS）和学术部门：杜克大学在这两个领域都是国际公认的领导者，但他们的集体优势尚未应用于解决成瘾决策的核心问题。这些领域现有多个机构实力雄厚，包括神经经济研究中心 (CNS)、认知神经科学中心 (CCN)、NIDA 支持的转化预防研究中心 (TPRC)、杜克大学尼古丁和吸烟中心戒烟研究 (CNSCR)、福卡商学院以及神经生物学、精神病学、心理学和神经科学系内强大的行为神经科学小组。尽管有这些优势，但根本性差距仍然存在。拟议的核心中心将填补杜克大学决策研究界的重要空白，带来重要且前沿的研究能力，并将加强杜克大学作为这一重要研究领域领先机构之一的地位。它将为本科神经科学专业和更广泛的研究生培训带来新的教学能力。最后，它将为 DIBS 与神经科学的社会相关应用提供一个重要的新链接，这与杜克大学“社会服务中的知识”的战略目标相一致。 NIDA P30 核心中心将使杜克大学能够立即填补这些空白，并通过聘请两个新院系来促进这些不同群体的整合，每个院系都带来新的专业知识，以桥接杜克大学当前的神经经济学和成瘾研究。