Neurohormonal Effects of Massage Therapy

按摩疗法对神经激素的影响

• 批准号: 7011268
• 负责人: Tiffany M. Field
• 金额: $ 18.45万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-02-01 至 2008-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7011268
• 关键词: alternative medicine; chemoprevention; clinical research; cortisol; disease /disorder prevention /control; female; human pregnant subject; human subject; human therapy evaluation; major depression; massage therapy; neurohormones; norepinephrine; patient oriented research; premature infant human; premature labor; prenatal care; women' s health

DESCRIPTION (provided by applicant): Over the last several years I have developed a program of research and a group of Touch Research Institutes to conduct research on touch therapies including the use of massage therapy for: 1) depressed pregnant women to prevent prematurity and 2) enhancing growth and development of preterm infants. In these studies positive effects unique to the different conditions have resulted from massage therapy. Following on the publication of these empirical data, replications are needed, and the potential underlying phenomena need further exploration. The specific aims of this KO5 application are to explore potential underlying mechanisms that might explain the effects of massage therapy on the two conditions of preventing prematurity in infants of depressed mothers and enhancing growth and development in preterm infants. Two research projects will be conducted on different conditions including 1) pregnancy massage to prevent prematurity and 2) preterm infant massage to enhance growth and development. For both projects a massage therapy and a standard treatment control group will be compared in a group analysis model. Path analyses will also be used to test hypothesized underlying mechanism models. The pregnancy massage project has just been funded by the March of Dimes, and the preterm infant massage project just received NIH funding. In addition, I would receive summer term mentoring and would spend time planning collaborative studies with Dr. Kerstin Uvnas-Moberg on mechanisms underlying stimulation/growth relationship including oxytocin and learning aspirate techniques for assessing food absorption hormones and Dr. Vivette Glover on factors contributing to prematurity including elevated norepinephrine and cortisol and the resulting uterine artery resistance and the technology for measuring that resistance. The K05 would allow me to increase my research time including being mentored and mentoring students from 25 to 75% time.

描述（由申请人提供）：在过去的几年里，我制定了一个研究计划和一组触摸研究所，以进行触摸疗法的研究，包括使用按摩疗法：1）抑郁的孕妇预防早产，2） ）促进早产儿的生长和发育。在这些研究中，按摩疗法针对不同的情况产生了独特的积极效果。这些经验数据发布后，需要进行复制，并且需要进一步探索潜在的潜在现象。该 KO5 应用的具体目的是探索潜在的潜在机制，这些机制可能解释按摩疗法对预防抑郁母亲的婴儿早产和促进早产儿生长发育这两种情况的影响。两个研究项目将针对不同的情况进行，包括1）怀孕按摩以预防早产和2）早产儿按摩以促进生长和发育。对于这两个项目，按摩疗法和标准治疗对照组将在组分析模型中进行比较。路径分析还将用于测试假设的基础机制模型。怀孕按摩项目刚刚获得了March of Dimes的资助，早产儿按摩项目刚刚获得了NIH的资助。此外，我将接受夏季学期指导，并花时间计划与 Kerstin Uvnas-Moberg 博士合作研究刺激/生长关系的潜在机制，包括催产素和学习评估食物吸收激素的抽吸技术，以及与 Vivette Glover 博士合作研究促进生长的因素。早产包括去甲肾上腺素和皮质醇升高以及由此产生的子宫动脉阻力以及测量该阻力的技术。 K05 可以让我增加研究时间，包括指导学生和指导学生的时间从 25% 增加到 75%。