C:C- BIOSTATISTICS

C:C-生物统计学

• 批准号: 7900981
• 负责人: Jane Meza
• 金额: $ 9.22万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7900981
• 关键词: Animals; Archives; Biometry; Biostatistics Core; Characteristics; Clinical Research; Complex; Conduct Clinical Trials; Data; Data Analyses; Databases; Detection; Development; Doctor of Philosophy; Ensure; Faculty; Housing; Laboratories; Malignant neoplasm of gastrointestinal tract; Malignant neoplasm of pancreas; Manuscripts; Monitor; Monitoring Clinical Trials; Nature; Patients; Protocols documentation; Public Health; Reporting; Reproduction spores; Research; Research Design; Research Personnel; Research Project Grants; Resources; Specific qualifier value; Training; UNMC Eppley Cancer Center; abstracting; base; college; data acquisition; design; human subject; improved; meetings; patient safety; success

Core C - Biostatistics The Biostatistics Core will develop statistical designs, develop statistical analysis plans, perform data acquisition, develop databases, archive data, develop protocol specific clinical research forms, perform data monitoring for clinical trials involving human subjects, perform data analysis and interpretation and aid in the development of manuscripts, abstracts and presentations. The specific aims of the Biostatistics Core are: Aim 1: Collaborate with SPORE investigators on study design to develop projects with appropriate statistical operating characteristics. Aim 2: Provide a statistical analysis plan for each SPORE project. Aim 3: Perform statistical analyses of project results as specified in the statistical analysis plan and collaborate with SPORE investigators on the interpretation and reporting of research findings. Aim 3: Monitor the conduct of SPORE clinical research projects to ensure patient safety and the scientific integrity of the projects. Aim 4: Collaborate with SPORE investigators on interpretation of data analysis results and aid in the development of manuscripts, abstracts and presentations. The Biostatistics Core will provide investigators with the biostatistical and computing expertise that is essential to the design of laboratory-based and clinical studies because it ensures the efficient use of financial, animal and patient resources while minimizing the likelihood of false conclusions. The projects of this SPORE will generate complex data that will require substantial biostatistical and computing input to be effectively analyzed and presented.

核心 C - 生物统计学 生物统计学核心将开发统计设计、制定统计分析计划、执行数据 采集、开发数据库、存档数据、开发协议特定的临床研究表格、执行数据 监测涉及人类受试者的临床试验，进行数据分析和解释，并协助 手稿、摘要和演示文稿的编写。生物统计学核心的具体目标是： 目标 1：与 SPORE 研究人员合作进行研究设计，以开发具有适当统计数据的项目 经营特点。 目标 2：为每个 SPORE 项目提供统计分析计划。 目标 3：按照统计分析计划的规定对项目结果进行统计分析 与 SPORE 研究人员合作解释和报告研究结果。 目标 3：监控 SPORE 临床研究项目的实施，确保患者安全和科学性 项目的完整性。 目标 4：与 SPORE 研究人员合作解释数据分析结果并协助 手稿、摘要和演示文稿的编写。 生物统计核心将为研究人员提供生物统计和计算专业知识 对于基于实验室和临床研究的设计至关重要，因为它确保了有效利用 财务、动物和患者资源，同时最大限度地减少错误结论的可能性。的项目 该孢子将生成复杂的数据，需要大量的生物统计和计算输入 有效地分析和呈现。