THE ROLE OF NMDA RECEPTORS DURING DIFFERENTIATION OF SPATIAL AND CONDITIONED LEA

NMDA 受体在空间和条件性 LEA 分化过程中的作用

• 批准号: 7959615
• 负责人: CLIFF H SUMMERS
• 金额: $ 1.24万
• 依托单位: UNIVERSITY OF SOUTH DAKOTA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7959615
• 关键词: Adaptive Behaviors; Amygdaloid structure; Behavior; Computer Retrieval of Information on Scientific Projects Database; Development; Funding; Goals; Grant; Hippocampus (Brain); Institution; Investigation; Process; Research; Research Personnel; Resources; Rodent Model; Role; Source; Stress and Coping; United States National Institutes of Health; Work; neurochemistry; neuromechanism; receptor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The goal of the proposed work is to develop a rodent model of stress coping that involves choice. The development of a rodent model is meant to allow for more detailed neurochemical investigations of adaptations of the amygdala and hippocampus that determine which behavior is expressed. The long-term objective is to compare hippocampal and amygdalar activity during the process of choosing socially adaptive behavior.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 拟议工作的目标是开发一种涉及选择的压力应对啮齿动物模型。 啮齿动物模型的开发旨在对杏仁核和海马体的适应进行更详细的神经化学研究，从而确定表达哪种行为。 长期目标是比较选择社会适应行为过程中海马和杏仁核的活动。