CTSA INFRASTRUCTURE FOR AIDS RESEARCH

CTSA 艾滋病研究基础设施

• 批准号: 8173795
• 负责人: Pamela B Davis
• 金额: $ 160.53万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8173795
• 关键词: Acquired Immunodeficiency Syndrome; Research; Research Infrastructure

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. Translational and clinical research are the crowning glories of biomedical research, but the infrastructure for this research has not received appropriate attention. In the Case Western Reserve University/Cleveland Clinic CTSA (the CTSA) we will coordinate existing resources relevant to clinical research at Case Western Reserve University and three of its hospital affiliates, the Cleveland Clinic, MetroHealth Medical Center, and University Hospitals Case Medical Center, including three existing GGRC facilities, a successful multidisciplinary institutional K12 program, substantial technological and statistical core facilities that currently exist in silos, and our famous practice-based research networks. In addition, we will create new resources, including community partnership resources, a new coordinated bioinformatics infrastructure, a new M.D-Ph.D. program in clinical research, and coordinated resources in bioethics and regulatory support. An academic home for clinical research, the Center for Clinical Investigation, directed by the CTSA PI and Interim Dean of the Case School of Medicine, will provide the career development support necessary for clinical investigators. When it is fully operational, the CTSA will offer research participant resources that span the range of support for technology-intensive studies that require the resource of the Academic Medical Centers, to local practices, to the Cleveland community itself. The community, both organizations and individuals, will be engaged in a dialogue about patient-based research. These participant resources will be supported by technologic cores, methodologic development, and an infrastructure of biomedical informatics. Permeating the entire enterprise is an educational program, directed by the CTSA Co-Pi, that takes full advantage of not only our institutional educational prowess, but also the CTSA clinical research resources. CTSA resources will be easily accessed either online or in person through a Clinical Research Concierge, which will assure prospective input into proposals by statistics and design experts, ethicists:and regulatory experts, and any other expertise that the project requires. Streamlining of operations and coordination of resources, set against a backdrop and track record of strong cooperation among the CTSA partners, will lead to efficient use of scarce resources and maximal support of clinical research in the city of Cleveland, which ultimately will benefit our citizens and the health of all Americans.

该子项目代表CTSA资金百分比的估计值 被用于广泛的研究领域（艾滋病研究，儿科研究或 临床试验）。 列出的总成本只是CTSA数量的估计值 基础设施朝向这一研究领域，而不是直接提供的资金 NCRR授予subproject或subproject人员。 翻译和临床研究是生物医学研究的冠军，但是这项研究的基础设施尚未得到适当的关注。在西部储备大学/克利夫兰诊所CTSA（CTSA）的情况下，我们将协调与凯斯西部储备大学及其三家医院分支机构，克利夫兰诊所，Metrohealth Medical Center和University Hospitals Case Medical Center相关的现有资源基于实践的研究网络。此外，我们将创建新的资源，包括社区伙伴关系资源，新的协调生物信息学基础架构，新的M.D-PH.D。临床研究计划，并协调了生物伦理学和监管支持的资源。由CTSA PI和医学院临时院长指导的临床研究中心的临床研究中心将为临床研究人员提供所需的职业发展支持。当它完全运行时，CTSA将提供研究参与者资源，这些资源涵盖了对技术密集型研究的支持范围，这些研究需要学术医疗中心，当地实践，克利夫兰社区本身的资源。组织和个人都将进行有关基于患者的研究的对话。这些参与者资源将得到技术核心，方法论发展和生物医学信息学基础设施的支持。渗透整个企业是由CTSA Co-Pi执导的教育计划，不仅可以充分利用我们的机构教育能力，而且还利用了CTSA临床研究资源。 CTSA资源将通过临床研究礼宾轻松地在线或亲自获取，这将确保统计和设计专家，道德专家和监管专家以及该项目所需的任何其他专业知识，以确保对建议的预期投入。在CTSA合作伙伴之间的背景和牢固合作的记录中，精简运营和资源协调将导致克利夫兰市有效利用稀缺资源和最大程度地支持临床研究，这最终将使我们的公民和所有美国人的健康受益。