Computational Resource and Dissemination Core

计算资源与传播核心

• 批准号: 7786687
• 负责人: MARIE DAVIDIAN
• 金额: $ 28.05万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2015-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7786687
• 关键词: Address; Adopted; Advocate; Clinical Trials; Code; Collaborations; Communities; Computer software; Data; Data Analyses; Development; Documentation; Educational workshop; Ensure; Evaluation; Generic Drugs; Goals; Information Technology; Language; Mails; Malignant Neoplasms; Methodology; Methods; Mission; Modification; Outcome; Process; Production; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Source; Source Code; Statistical Methods; System; Testing; Update; anticancer research; computing resources; design; evaluation/testing; innovation; programs; simulation; software development; tool; user friendly software; user-friendly; web interface

The overall scientific goal of this ambitious Program Project is to develop innovative statistical methods for cancer clinical trials that can help to hasten successful introduction of effective new therapies into practice The Computational Resource and Dissemination Core (Core C) will carry out several critical functions related to the implementation and dissemination of the statistical methods for the design and analysis of cancer clinical trials developed in the five research projects. The Core will be tasked with developing, in close collaboration with project investigators, efficient, robust code implementing the statistical methods that can be used for evaluation of the methods in extensive simulation studies and for application of the methods to data compiled by Core B and from other sources. The Core will also be tasked with leading and facilitating, in close collaboration with project investigators, development of robust, reliable, user-friendly, and welldocumented software applications suitable for public dissemination to practitioners involved in the design and analysis of cancer clinical trials. Core C wili adopt best practices for these tasks and provide the necessary information technology and educational infrastructure to disseminate these applications.

这个雄心勃勃的计划项目的总体科学目标是开发创新的统计方法 癌症临床试验，可以帮助成功将有效的新疗法成功引入实践 计算资源和传播核心（核心C）将执行几个关键功能 实施和传播癌症设计和分析的统计方法 在五个研究项目中开发了临床试验。核心将负责开发， 与项目调查人员的合作，高效，可靠的代码，以实施可以实施的统计方法 用于评估广泛的模拟研究中的方法，并应用方法 由核心B和其他来源编译的数据。核心也将负责领导和促进， 与项目调查人员密切合作，发展强大，可靠，用户友好且文献充裕 软件应用程序适用于参与设计的从业者的公共传播 和癌症临床试验的分析。核心C Wili采用这些任务的最佳实践，并提供 必要的信息技术和教育基础设施，以传播这些应用。