CORE--Genetics

核心——遗传学

• 批准号: 7798006
• 负责人: Mark Mariusz Bouzyk
• 金额: $ 6.45万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7798006
• 关键词: Agreement; Asthma; Candidate Disease Gene; Core Facility; Data; Data Quality; Diabetes Mellitus; Disease; Doctor of Philosophy; Ensure; Equipment; Europe; Faculty; Genetic; Genomics; Genotype; Housing; Human Resources; Industry; Laboratories; Life Cycle Stages; Link; Mediation; Medical center; Methods; National Institute of Neurological Disorders and Stroke; Neurosciences; Pharmacologic Substance; Positioning Attribute; Process; Research Infrastructure; Sampling; Science; Services; Time; Work; data management; flexibility; genetic linkage; genome wide association study; new technology

Mark Bouzyk, PhD will serve as the Genetics Core Director. Dr. Bouzyk is the director of the Emory Center for Medical Genomics (CMG), which will house and administer the Genetics Core. The core provides state-of-theart laboratory capabilities to enable high throughput genetic linkage and association studies ranging from candidate gene to genomic screens all supported by a robust and flexible data management infrastructure. Dr Bouzyk recently joined the faculty at Emory with a more than eight year track record in a global pharmaceutical company, GlaxoSmithKline, where he served as Director of Genetic Laboratory Sciences leading the company's high throughput genotyping efforts in Europe. During his time in industry, Dr Bouzyk not only established and managed the high throughput genetic laboratories for GSK, including DMA sample management, sequencing and genotyping, he also delivered key processes for candidate gene and whole genome association studies as well as negotiating key scientific & technological agreements for such genetic projects. This has resulted in an annual turnover of more than 10 million genotypes at GSK with significant preliminary association data in several common diseases, such as diabetes and asthma. In his position at Emory, Dr. Bouzyk serves as the link between the faculty utilizing the services of the core and the technicians analyzing the samples. Under his direction, the Center for Medical Genomics has acquired the equipment and personnel necessary to operate as a high-throughput extraction, sequencing, expression and genotyping facility. Dr. Bouzyk is responsible for working with the faculty to develop workflows for the life cycle of each project, to develop methods to ensure high quality of the data produced by the core, and to identify and acquire new technology and equipment.

Mark Bouzyk博士将担任遗传学核心主任。 Bouzyk博士是Emory医学基因组学中心（CMG）的主任，该中心将容纳并管理遗传学核心。核心提供了最先进的实验室能力，以使高吞吐量遗传联系和关联研究从候选基因到基因组筛查，所有这些筛查都得到了强大而灵活的数据管理基础结构的支持。 Bouzyk博士最近在埃默里（Emory）的教职员工加入了一家全球制药公司GlaxoSmithkline的八年以上记录，他曾担任遗传实验室科学主任，领导该公司在欧洲的高通量基因分类工作。 Bouzyk博士在行业期间，不仅建立并管理了GSK的高吞吐量遗传实验室，包括DMA样本管理，测序和基因分型，还为候选基因和整个基因组协会研究以及协商此类遗传学的关键科学和技术协议提供了关键过程 项目。这导致在GSK的年营业额度超过1000万个基因型，并在几种常见疾病（例如糖尿病和哮喘）中具有显着的初步关联数据。在埃默里（Emory）的职位上，布齐克（Bouzyk）博士是利用核心服务的教师与分析样品的技术人员之间的联系。在他的指导下，医学基因组学中心已经获得了作为高通量提取，测序，表达和基因分型设施所必需的设备和人员。 Bouzyk博士负责与教师合作，为每个项目的生命周期开发工作流程，以开发方法，以确保核心产生的数据高质量，并识别和获取新的技术和设备。