METABOLIC SYNDROME IN HIV-INFECTED PATIENTS FROM AN URBAN, MIDWESTERN US

美国中西部城市艾滋病毒感染者的代谢综合征

• 批准号: 7953986
• 负责人: KRISTIN E. MONDY
• 金额: $ 0.31万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-02-01 至 2010-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7953986
• 关键词: Age; Cardiovascular Diseases; Clinic; Comorbidity; Computer Retrieval of Information on Scientific Projects Database; Cross-Sectional Studies; Data; Data Files; Evaluation; Funding; Grant; HIV; Health Surveys; Highly Active Antiretroviral Therapy; Institution; Laboratories; Mass Spectrum Analysis; Metabolic syndrome; National Health and Nutrition Examination Survey; Outpatients; Patients; Persons; Race; Research; Research Personnel; Resources; Risk; Risk Factors; Source; Tobacco use; United States National Institutes of Health; Virus Diseases; biomedical resource; cohort; prospective; sex

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. BACKGROUND: The association between the use of highly active antiretroviral therapy (HAART) and an increased risk of metabolic syndrome and cardiovascular disease remains unclear. METHODS: We conducted a prospective, cross-sectional study of the risk factors associated with metabolic syndrome and cardiovascular disease among patients from an urban outpatient human immunodeficiency virus (HIV) clinic. Evaluation included laboratory data that were obtained after an overnight fast and a health survey that assessed traditional risk factors associated with cardiovascular disease, HIV-related factors, and comorbidities. Data collected were compared with data files from a cohort from the National Health and Nutrition Examination Survey (NHANES; 2001-2002) of persons who were seronegative for HIV infection who were matched for age, sex, race, and tobacco use.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 背景：使用高效抗逆转录病毒疗法（HAART）与代谢综合征和心血管疾病风险增加之间的关系仍不清楚。方法：我们对城市人类免疫缺陷病毒（HIV）门诊患者的代谢综合征和心血管疾病相关危险因素进行了一项前瞻性横断面研究。评估包括隔夜禁食后获得的实验室数据以及评估与心血管疾病、艾滋病毒相关因素和合并症相关的传统危险因素的健康调查。将收集的数据与国家健康和营养检查调查（NHANES；2001-2002）的一组数据文件进行比较，这些数据文件的年龄、性别、种族和吸烟情况相匹配，HIV感染血清呈阴性。