INTERNET BASED TOOLS RESOURCE FOR PROTEIN MASS SPECTROMETRY

基于互联网的蛋白质质谱工具资源

• 批准号: 7954056
• 负责人: JULIO C PADOVAN
• 金额: $ 1.19万
• 依托单位: ROCKEFELLER UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-03-01 至 2010-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7954056
• 关键词: Affect; Algorithms; Amino Acid Sequence; Amino Acids; Bioinformatics; Chemicals; Collection; Computer Retrieval of Information on Scientific Projects Database; Cross-Linking Reagents; Databases; Disulfides; Funding; Grant; Institution; Internet; Libraries; Maps; Mass Spectrum Analysis; Modification; Peptide Mapping; Peptide Sequence Determination; Peptides; Probability; Process; Protein Sequence Analysis; Proteins; Research; Research Personnel; Resources; Retrieval; Source; United States National Institutes of Health; base; crosslink; design; disulfide bond; macromolecule; oxidation; polypeptide; protein aminoacid sequence; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We continue to maintain an internet based bioinformatic resource for protein mass spectrometry. These tools ca be found at the universal resource locator http://www.rockefeller.edu/labheads/chait/tools.php and include: ProFound ProFound is a tool for searching a protein sequence collections with peptide mass maps. A Bayesian algorithm is used to rank the protein sequences in the database according to their probability of producing the peptide map. ProteinInfo ProteinInfo is a collection of tools for retrieval and analysis of protein sequences. The capabilities of the analysis tools include peptide mapping, mass spectrometric fragmentation analysis, disulfide mapping, etc. PeptideMap PeptideMap is a tool for finding modifications on polypeptide sequences. The modifications can be affecting single amino acids (e.g. phoshorylation or oxidation) or cross-linking two amino acids (e.g. disulfide bonds or chemical cross-linking reagents). PepFrag PepFrag is a tool for identifying proteins from a collection of sequences that matches a single tandem mass spectrum. X! Tandem X! Tandem is a tool for identifying proteins from a collection of peptide sequences that matches tandem mass spectra. X! Hunter X! Hunter is a tool for identifying proteins that matches tandem mass spectra to a library of spectra that have been confidently assigned to a particular peptide sequence. GPMDB GPMDB is a database of tandem mass spectra and their assigned peptide sequences. It is designed to aid in the difficult process of validating peptide MS/MS spectra. NCDIR Strain Database The National Center for Dynamic Interactome Research (NCDIR) Strain Database

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 我们继续维护基于互联网的生物信息学资源，用于蛋白质质谱。 这些工具可以在通用资源定位器http://www.rockefeller.edu/labheads/chait/chait/tools.php上找到： 深刻的 深刻是搜索具有肽质量图的蛋白质序列集合的工具。贝叶斯算法根据其产生肽图的可能性来对数据库中的蛋白质序列进行排名。 蛋白质 Protininfo是用于检索和分析蛋白质序列的工具集合。分析工具的功能包括肽映射，质谱片段分析，二硫化物映射等。 peptidemap PeptidEmap是用于查找多肽序列修改的工具。修饰可能会影响单个氨基酸（例如磷酸化或氧化）或交联两个氨基酸（例如二硫键或化学交联试剂）。 pepfrag Pepfrag是一种用于识别与单个串联质量谱匹配的序列集合中的蛋白质的工具。 x！串联 x！串联是一种用于识别与串联质谱匹配的肽序列集合中的蛋白质的工具。 x！猎人 x！ Hunter是一种识别蛋白质的工具，该蛋白质将串联质谱与光谱库相匹配，这些光谱已自信地分配给特定的肽序列。 GPMDB GPMDB是串联质谱的数据库及其分配的肽序列。它旨在帮助验证肽MS/MS光谱的困难过程。 NCDIR应变数据库 国家动态互动研究中心（NCDIR）应变数据库