Murine Genetics Core

小鼠遗传学核心

• 批准号: 7799166
• 负责人: CAROLYN CRAY
• 金额: $ 10.52万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7799166
• 关键词: Adherence; Age; Animal Husbandry; Animals; Antibodies; Breeding; Budgets; Censuses; Ensure; Genetic; Grant; Health; Housing; Individual; Knockout Mice; Mouse Strains; Mus; Mutation; Mycoplasma; Parasites; Participant; Phenotype; Protocols documentation; Regulation; Research Project Grants; Resources; Rodent; Running; Schedule; Screening procedure; Secure; Services; Transgenes; Transgenic Mice; Transgenic Organisms; Tumor Cell Line; Tumor Immunity; Universities; Viral; Virus; animal breeding; animal care; animal facility; base; congenic; design; mouse model; programs; research study; sex; tumor

The Murine Genetics Core is designed to provide centralized and specialized animal breeding and screening of several strains of mice. Breeding of immunodeficient and transgenic mice is required for the studies in all the projects. Many of the strains are not commercially available or are not readily available in numbers needed by the studies. These strains will be bred and genetically screened by the core. The core will also oversee the husbandry of the animals and periodically screen them to ensure that they are parasite free as well as virus and mycoplasma antibody free. In addition, the core will also provide screening services for the review of the many tumor cell lines which will be used in the various projects.

鼠遗传学核心旨在提供集中和专业的动物育种和筛查 几只小鼠菌株。在所有研究中，都需要进行免疫缺陷和转基因小鼠的繁殖 项目。许多菌株不可商购或数字不容易获得 研究需要。这些菌株将被堆积并通过核心筛选。核心也将 监督动物的饲养，并定期筛选它们，以确保它们没有寄生虫 以及无病毒和支原体抗体。此外，核心还将为 对各种项目中都使用的许多肿瘤细胞系的综述。