Community Child Health Network, Eastern North Carolina

北卡罗来纳州东部社区儿童健康网络

• 批准号: 7893040
• 负责人: John M Thorp
• 金额: $ 44.78万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7893040
• 关键词: Affect; African American; Asthma; Baltimore; Behavioral; Birth; Child; Child Development; Child Language; Child health care; Cognitive; Cohort Studies; Communities; Community Networks; Community Participation; Conceptions; County; Development; Disease; District of Columbia; Economic Factors; Enrollment; Etiology; Exposure to; Family; Fathers; Fetal Growth Retardation; Fostering; Future; Growth; Health; Health Services Accessibility; Health Services Research; Health behavior; Healthcare; Hispanics; Human; Infant Mortality; Intervention Studies; Language; Language Development; Life; Live Birth; Longitudinal Studies; Los Angeles; Love; Low income; Maternal and Child Health; Measures; Mediating; Mental Health; Monitor; Mothers; Multiple Pregnancy; Nature; Neighborhoods; North Carolina; Outcome; Overweight; Parenting behavior; Parents; Pathway interactions; Performance; Phase; Play; Pregnancy; Pregnancy Interval; Pregnancy Outcome; Pregnancy Trimesters; Premature Birth; Preventive Intervention; Research; Research Personnel; Research Project Grants; Respiratory physiology; Risk; Risk Factors; Role; Rural; Schools; Science; Services; Site; Specific qualifier value; Specificity; Strategic Planning; Stress; Testing; Time; Universities; Women' s Health; allostatic load; base; cohort; community based participatory research; community living; design; early childhood; early onset; fetal programming; health disparity; improved; innovation; insight; medical schools; multidisciplinary; postnatal; pregnant; premature; prenatal; programs; psychosocial; racial and ethnic; racism; resilience; social; socioeconomics; suburb; systemic intervention; theories

DESCRIPTION (provided by applicant): The Community Child Health Network (CCHN) Phase II research proposes to: (1) advance understanding of the combined biomedical, social, behavioral, and environmental influences on the course of prenatal development, pregnancy outcome, and early child development, particularly in physical growth, respiratory function, and language development. CCHN proposes a 5-site, longitudinal study of 2 integrated cohorts: a Birth Cohort Study of 5250 families (1050 per site) followed by a Subsequent Birth Study (38 percent of mothers expected to have a subsequent live birth). These studies focus on the role of stress and allostatic load, as moderated by resilience and supports, on pregnancy outcome, fetal programming, and child development outcomes of prematurity/intrauterine growth restriction, overweight, asthma, and language and cognitive development; and (2) to develop and document active community participation in all phases of the study through the community based participatory research (CBPR) in the community-academic partnerships (CAPs). The findings are intended to advance theory about the etiology and impact of health disparities related to pregnancy and early childhood outcomes, as well as inform the design of future preventive interventions. Innovative features include: 1) focus on the inter- and pre-conception period; 2) combining biomedical and psychosocial indicators and outcomes within an integrated conceptual framework; 3) multidisciplinary measures of resilience and supports as well as risks; 4) including fathers as integral to both pregnancy and child health outcomes; and 5) a participatory research partnership of the community and university at local sites and the national network. North Carolina persists in having maternal and child health disparities in preterm birth, infant mortality, and access to health care. These poor birth outcomes disproportionately affect families in the predominately rural Eastern part of the state. Partnered together in this community based, multilevel research project will be the UNC Center for Women's Health, the UNC Cecil G. Sheps Center for Health Services Research, East Carolina University School of Medicine and School of Health and Human Performance, as well as the Eastern North Carolina Baby Love Plus Project. Eastern NC community partners have participated fully in the research planning and will have crucial roles to play in the initiation, conduct, and analyses, of this cohort study

描述（由申请人提供）：社区儿童健康网络（CCHN）第二阶段研究提出：（1）提前了解生物医学，社会，行为和环境的组合对产前发展，妊娠结局和早期儿童发展的影响，尤其是在身体成长，呼吸功能和语言发展方面。 CCHN提出了2个综合队列的5个站点的纵向研究：一项针对5250个家庭的出生队列研究（每个站点1050个），然后进行随后的出生研究（预计有38％的母亲预计将有后期出生）。这些研究着重于应激和同性载荷的作用，这是由于韧性和支持，对怀孕结果，胎儿编程以及早产的儿童发展结果的主持/宫内内生长限制，超重，哮喘以及语言和认知发展； （2）通过基于社区的参与研究（CBPR）在社区学术伙伴关系（CAPS）中开发和记录研究的积极参与研究的各个阶段。这些发现旨在推进有关与怀孕和幼儿结局有关的健康差异的病因和影响的理论，并为未来的预防干预措施设计。创新特征包括：1）关注概念和概念前时期； 2）将生物医学和社会心理指标和结果结合在一个综合的概念框架中； 3）弹性和支持的多学科措施以及风险； 4）包括父亲，是怀孕和儿童健康成果不可或缺的一部分； 5）社区和大学在本地网站和国家网络的参与研究合作伙伴关系。北卡罗来纳州一直在早产，婴儿死亡率和获得医疗保健方面的孕产妇和儿童健康差异。这些较差的出生结果不成比例地影响该州东部地区主要农村地区的家庭。在这个基于社区的多层次研究项目中合作，将是UNC妇女健康中心，UNC Cecil G. Sheps卫生服务中心，东卡罗来纳州大学医学院医学院和卫生与人类绩效学院以及北卡罗来纳州东部的Baby Love Plus Project。东北北卡罗来纳州社区合作伙伴已经完全参与了研究计划，并将在本研究研究中发挥至关重要的作用，进行和分析。