Core A

核心A

• 批准号: 8102898
• 负责人: Steven Daniel Douglas
• 金额: $ 17.25万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8102898
• 关键词: AIDS neuropathy; Clinical; Collaborations; Communication; Decision Making; Development Plans; Expenditure; Fostering; Goals; Guidelines; Individual; Information Dissemination; Institution; Intellectual Property; Leadership; Mission; National Institute of Mental Health; Participant; Policies; Principal Investigator; Procedures; Process; Program Development; Publications; Research; Research Activity; Research Personnel; Research Priority; Resource Allocation; Resources; Role; Scientist; Services; Specific qualifier value; Supervision; Technology Transfer; Therapeutic; TimeLine; U-Series Cooperative Agreements; United States National Institutes of Health; data sharing; design; drug development; innovation; meetings; novel; operation; pre-clinical; programs; research study; response

Core A will serve all projects and cores in the Novel neuroAIDS Therapies: Integrated Preclinical/Clinical IPCP and will be responsible for oversight ofthe scientific, administrative, regulatory and operational aspects of the program's activities. The overall goal of the Administrative Core is to enable the IPCP to fulfill its scientific mission, as defined in the introduction and overview at the beginning of this proposal, as a specified in the Specific Aims of the three projects. The Principal Investigator, Dr. Steven D. Douglas, will direct this core and will provide leadership, direction, and organization to the overall program project effort and assist each of the Project Leaders and Core Leaders in the successful execution of their planned experiments or support services. The objectives ofthe Administrative Core are to: (1) Coordinate and supervise this IPCP; (2) Oversee the development plan ofthe IPCP by coordinating regular review of study results and integration of this information into the decision-making process that is integral to the drug development mission of the research program; (3) Promote a high degree of collaboration and synergistic interaction among the investigators and core leaders; (4) Facilitate participation of this IPCP within NIH IPCP Program activities; (5) Insure efficient and appropriate use of core services by the individual projects; (6) Provide investigators and core directors with timely and accurate information regarding core and project expenditures and resources; (7) Insure that the program's development plan is conducted in compliance with all applicable regulatory guidelines and NIH policies and procedures; (8) Organize and implement regular internal and external oversight of the IPCP's activities; and, (9) Support the program in fulfilling its obligations related to information dissemination, scientific publication and data sharing. This will include management of intellectual property issues in collaboration with the CHOP Department of Technology Transfer. The Administrative Core will be utilized equally by all participating projects and scientific cores.

核心A将为新型神经辅助疗法中的所有项目和核心服务：综合临床前/临床 IPCP并将负责监督科学，行政，监管和运营方面 该计划的活动。行政核心的总体目标是使IPCP能够实现其 根据本提案开始的引言和概述所定义的科学任务，如指定 在这三个项目的具体目标中。首席调查员史蒂文·道格拉斯（Steven D. Douglas）博士将指导此 核心，并将为整体计划项目努力提供领导，指导和组织 在成功执行计划的实验或 支持服务。管理核心的目标是：（1）协调和监督此IPCP； （2）通过定期审查研究结果和整合来监督IPCP的开发计划 这些信息涉及决策过程，这是药物开发任务不可或缺的任务 研究计划； （3）促进高度的协作和协同互动 调查人员和核心领导者； （4）促进该IPCP参加NIH IPCP计划活动； （5） 确保各个项目有效且适当地使用核心服务； （6）提供调查人员和 有关核心和项目支出和资源的核心主管，具有及时准确的信息； （7）确保按照所有适用的监管进行计划的制定计划 指南和NIH政策和程序； （8）组织和实施常规内部和外部 监督IPCP活动； （9）支持该计划以履行其义务 信息传播，科学出版物和数据共享。这将包括管理 知识产权问题与CHOP技术传输部合作。这 所有参与的项目和科学核心将同样利用行政核心。