FASEB Conference: Renal Hemodynamics: Biomolecular Control Mechanisms Integrating

FASEB 会议：肾血流动力学：生物分子控制机制整合

基本信息

批准号：
7329023
负责人：
WILLIAM J ARENDSHORST
金额：
$ 1.3万
依托单位：
FEDERATION OF AMER SOC FOR EXPER BIOLOGY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-07-01 至 2008-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7329023
关键词：
Academy Area Armin Australia Award Berlin Biomedical Research Blood Vessels Carbon Monoxide Cities Clinical Committee Members Denmark Depth Diabetes Mellitus Disease Eicosanoids Endothelin Excretory function Faculty Feedback Fostering Genetic Germany Goals Hand Homeostasis Human Resources Hypertension Injury Iowa Japan Juxtaglomerular Apparatus Kidney Kidney Diseases Metabolic syndrome Molecular Natriuresis Nitric Oxide Norway Operative Surgical Procedures Oxidative Stress Paris, France Patients Physiological Principal Investigator Reactive Oxygen Species Recommendation Regulation Renal Circulation Renal Hypertension Renin-Angiotensin System Research Research Personnel Rivers Schedule Scientist Signal Pathway Signal Transduction Sodium Students Sweden Sympathetic Nervous System Time Translating Travel Tubular formation Underrepresented Minority Vascular resistance Vermont Woman authority experience hemodynamics kidney vascular structure member multidisciplinary performance site planetary Atmosphere posters pressure programs symposium

项目摘要

DESCRIPTION (provided by applicant): The FASEB Summer Research Conference on "Renal Hemodynamics: Biomolecular Control Mechanisms Integrating Vascular and Tubular Function" is scheduled for July 7-12, 2007 at Vermont Academy, Saxtons River, VT. The overall goal of this informal meeting is to provide a forum for multidisciplinary scientists to meet and openly discuss their most current research in a casual, relaxed atmosphere. There is ample time for poster sessions which fosters in-depth discussions, with special featured poster "hot-topic" sessions highlighting the latest ongoing research of students, fellows and young investigators. Conference aims are: 1) to convene an internationally recognized multidisciplinary group of investigators to discuss current research findings in the area of microcirculatory biomolecular control mechanisms that integrate vascular and tubular function in the kidney, 2) to promote the participation of young scientists with special emphasis on women and under-represented minorities, through recruitment and a travel award program; and 3) to translate basic biomedical research in renal hemodynamic and tubular function to major patient diseases that include renal disease, diabetes, and hypertension. Specific topics to be covered include: genetic regulation of the renin-angiotensin system and signaling pathways in the juxtaglomerular apparatus, intrinsic autoregulatory mechanisms: myogenic signaling and tubuloglomerular feedback, dynamic autoregulation and modulation of mechanisms, regulation of the renal circulation and tubular transport by carbon monoxide / nitric oxide, the sympathetic nervous system, eicosanoids, endothelin and oxidative stress / reactive oxygen species, pressure natriuresis: physiological / pathophysiological importance and molecular mechanisms integrating effects of arterial pressure on tubular function and sodium excretion, abnormalities in the regulation of renal vascular resistance in hypertension, diabetes mellitus, and the metabolic syndrome, genetic influences in diabetes and hypertension, and mechanisms of renal injury.

描述（由申请人提供）： FASEB 夏季研究会议“肾脏血流动力学：整合血管和肾小管功能的生物分子控制机制”定于 2007 年 7 月 7 日至 12 日在佛蒙特州萨克斯顿河佛蒙特学院举行。这次非正式会议的总体目标是为多学科科学家提供一个论坛，让他们在轻松、轻松的氛围中会面并公开讨论他们最新的研究。有充足的时间进行海报会议，促进深入讨论，特别的海报“热点”会议强调学生、研究员和年轻研究人员正在进行的最新研究。会议目标是：1）召集国际公认的多学科研究人员小组，讨论整合肾脏血管和肾小管功能的微循环生物分子控制机制领域的当前研究成果，2）特别强调促进年轻科学家的参与通过招聘和旅行奖励计划，关注妇女和代表性不足的少数群体； 3）将肾脏血流动力学和肾小管功能的基础生物医学研究转化为主要患者疾病，包括肾脏疾病、糖尿病和高血压。涵盖的具体主题包括：肾素-血管紧张素系统的遗传调控和肾小球旁装置的信号通路、内在的自动调节机制：肌源性信号传导和肾小管肾小球反馈、动态自动调节和机制调节、肾循环的调节和碳的肾小管运输一氧化氮/一氧化氮、交感神经系统、类二十烷酸、内皮素和氧化应激/活性氧、压力尿钠：生理/病理生理学重要性和分子机制综合动脉压对肾小管功能和钠排泄的影响，高血压、糖尿病和代谢综合征中肾血管阻力调节异常，糖尿病和高血压的遗传影响以及肾损伤机制。