Therapeutical Profiles of Opioid Delta Receptors: New Modalities

阿片类药物 Delta 受体的治疗概况：新模式

• 批准号: 7513582
• 负责人: Frank Porreca
• 金额: $ 31.22万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7513582
• 关键词: Acute; Adrenergic Agents; Agonist; Animals; Antibodies; Behavioral; Binding; Biological Assay; Bolus Infusion; CALCA gene; Calcitonin Gene-Related Peptide; Cannabinoids; Capsaicin; Cells; Clinical; Complex; Coupling; Cultured Cells; Data; Development; Disruption; Dorsal; Dose; Down-Regulation; Dynorphins; Enkephalins; Exposure to; Fiber; GTP-Binding Proteins; Glutamates; Goals; Hand; Human; Hybrids; Hyperalgesia; Immunohistochemistry; Implant; Infusion procedures; Injection of therapeutic agent; Knock-out; Laboratories; Lesion; Lidocaine; Measurement; Measures; Mechanics; Mediating; Mediator of activation protein; Methods; Microinjections; Modality; Modeling; Monitor; Morphine; Nervous system structure; Opioid; Opioid Receptor; Pain; Pathway interactions; Peptides; Pharmacology, Other; Physiological; Placebos; Pre-Clinical Model; Rattus; Readability; Receptor Down-Regulation; Reporting; Role; S100A12 gene; Sensory; Sensory Thresholds; Signal Transduction; Site; Slice; Spinal; Spinal Cord; Spinal Ganglia; Stimulus; Substance P Receptor; Suggestion; System; Testing; Time; Tissues; Up-Regulation; Work; Writing; adrenergic; allodynia; arrestin 2; base; chronic pain; delta opioid receptor; dermorphin; dorsal horn; ganglion cell; glycyl-glycyl-glycyl-glycine; human S100A12 protein; immunoreactivity; in vivo; insight; knock-down; mu opioid receptors; novel; osmotic minipump; prevent; radioligand; receptor; receptor density; response; retrograde transport; sham surgery; subcutaneous