Cancer Genetics Career Development Program

癌症遗传学职业发展计划

基本信息

批准号：
7492856
负责人：
JEFFREY N WEITZEL
金额：
$ 8.57万
依托单位：
BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
依托单位国家：
美国
项目类别：
财政年份：
2001
资助国家：
美国
起止时间：
2001-02-08 至 2011-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7492856
关键词：
Academic Medical Centers Academic degree Achievement Address Advertising Advisory Committees Affect Ally American Appendix Applications Grants Arts Award Basic Science Bioinformatics Biological Sciences Biomedical Research Biometry Bone Marrow Transplantation Breast Cancer Prevention Trial Bypass Budget California Cancer Burden Cancer Genetics Education Program Cancer Research Project Carcinogen exposure Caring Categories Cell Differentiation process Cellular biology Charge Chemoprevention Cities Clinic Clinical Clinical Cancer Center Clinical Oncology Clinical Oncology Supplement (K12)Clinical Research Clinical Trials Collaborations Commit Communities Competence Comprehensive Cancer Center Consultations Core Facility County DNA Repair Data Depth Development Diagnostic Discipline Doctor of Philosophy Education Educational Curriculum Educational workshop Effectiveness Elements Enrollment Epidemiology Evaluation Extramural Activities Faculty Family Fellowship Fellowship Program Foundations Funding Future Gene Proteins Genes Genetic Genetic Counseling Genetic Engineering Genetic Programming Genetic Research Genetic Services Genetic screening method Genetic testing for cancer risk Genome Genomics Goals Grant Hand Health Health Benefit Health Personnel Health Professional Health Services Research Hematology Hematopathology Hereditary Malignant Neoplasm Hour Housing Image Individual Industry Informatics Information Sciences Inherited Institution Internet Internships Intervention Investigation Joints Journals Knowledge Laboratories Laboratory Study Leadership Learning Letters Los Angeles Malignant Neoplasms Master&apos s Degree Medical Medical Genetics Medical Oncology Medical center Mentored Clinical Scientist Development Program Mentors Mentorship Mission Molecular Genetics Molecular Medicine Monoclonal Antibodies Mutagenesis NIH Program Announcements National Cancer Institute National Comprehensive Cancer Network Nurses Nursing Education Research Operative Surgical Procedures Oranges Outcome Outcome Measure Participant Patient Care Peer Review Performance Physicians Pike fish Placement Play Population Positioning Attribute Postdoctoral Fellow Predisposition Preparation Prevention Prevention Research Prevention program Preventive Medicine Principal Investigator Productivity Professional Education Professional counselor Program Development Program Evaluation Progress Reports Proteomics Protocols documentation Public Health Publications Qualifying Quality of life RNA Processing Radioimmunotherapy Recruitment Activity Reporting Research Research Infrastructure Research Institute Research Personnel Research Project Grants Research Training Resources Risk Risk Assessment Risk Management Role Rotation SECTM1 gene Schools Scientist Screening for cancer Series Services Signal Transduction Site Social Aspects of Cancer Societies Solid Structure Students Supervision Surgical Oncologist Surgical Oncology Syndrome Testing Therapeutic Human Experimentation Therapeutic Intervention Thinking Time Training Training Programs Translating Translational Research Translations Underrepresented Minority Underserved Population United States National Institutes of Health Universities Update Visit Week Women&apos s Health Work abstracting anticancer research base bench to bedside cancer diagnosis cancer genetics cancer prevention cancer risk career clinical conference cohort concept cost day design education planning experience gene environment interaction gene therapy genetic epidemiology genetic technology improved innovation interest lectures malignant breast neoplasm medical schools member multidisciplinary oncology planetary Atmosphere post-doctoral training prevent professor programs psychosocial response skills success symposium tool

项目摘要

DESCRIPTION (provided by applicant): This is a competitive renewal application for an established cancer genetics career development program (CGCDP), the goal of which is to generate program leaders for cancer genetics and cancer prevention research. We need more leaders with focused interdisciplinary training to move the field of cancer genetics research forward. Cross training of researchers with different backgrounds is needed to leverage knowledge of genomics, proteomics, genetic epidemiology, cancer genetics and molecular medicine for translation to cancer prevention. The CGCDP is the only program of its kind in the NCI R25T portfolio. In the initial project period we achieved all of the objectives outlined in the original funded R25T proposal. We developed the infrastructure, a specialized curriculum, an effective advisory committee, and we established recruitment strategies and identified and reached the candidate applicant pool. We recruited twelve highly qualified trainees (4 MDs, 2 PhD nurses, 2 RNs, 4 genetic counselors)-3/6 doctoral trainees are under-represented minorities. Recruitment efforts included advertising in professional oncology and genetics journals, web listings, and a compelling program announcement posted at national meetings and disseminated to directors of 145 medical oncology and 60 genetics programs. A tailored education plan for each trainee provides 4 contact hrs coursework, 4 hrs experiential training, 5 hrs interdisciplinary clinical conference work, and a minimum of 26 hrs research experience/training every week. The specialized curriculum includes a new graduate course in clinical cancer genetics that was created and piloted in the first project period, and approved for permanent status on the curriculum at a regional university. Trainees learn to design and implement highly interdisciplinary collaborative cancer genetics and prevention research projects. Individual education plans emphasize interdisciplinary coursework and conferences, and focus on maturation of cancer research projects and preparation of a PHS 398 grant proposal. Trainees may concurrently pursue a master's degree with advanced course work. In the first funding period, trainee academic productivity was exceptional and resulted in 8 peer-reviewed publications. Every trainee presented one or more abstracts at professional meetings. Six trainee grant applications have resulted in extramural funding. CGCDP alumni are continuing on research career trajectories (8 of 9 alumni have taken academic and/or research positions, and one is involved in industry education), We are improving the specialized curriculum, introducing new cancer genetics-focused workshops and lectures, adding new research and cross-disciplinary training elements, and growing the roster of experienced, well-funded research mentors. There is a new visiting professors series to profile thought leaders and potential career trajectories in cancer genetics research, and new academic degree options in biological sciences and bioinformatics. The success of the CGCDP is reflected by trainee productivity and placement, and there is a continued critical need for health care professionals with research expertise in the emerging discipline of cancer genetics. Our new emphasis, exclusively on post-doctoral trainees recommended by the previous review, streamlines the program and concentrates resources on trainees most likely to become independent research scientists in cancer genetics. The graduates of this program will reduce the burden of cancer among those at highest risk by translating cancer genetic epidemiology to individual risk assessment tools and acceptable interventions.

描述（由申请人提供）：这是针对已建立的癌症遗传学职业发展计划（CGCDP）的竞争更新申请，其目的是为癌症遗传学和预防癌症的研究创造计划领导者。我们需要更多的领导者进行重点跨学科培训，以推动癌症遗传学研究的领域。需要对具有不同背景的研究人员进行交叉培训，以利用基因组学，蛋白质组学，遗传流行病学，癌症遗传学和分子医学的知识来转化为预防癌症。 CGCDP是NCI R25T投资组合中唯一同类程序。在最初的项目期间，我们实现了原始资助的R25T提案中概述的所有目标。我们开发了基础设施，专门的课程，一个有效的咨询委员会，我们建立了招聘策略，并确定并触及了候选人申请人池。我们招募了十二位高素质的学员（4名MD，2名Phd护士，2名RN，4位遗传顾问）-3/6博士学生的学员是代表不足的少数群体。招聘工作包括专业肿瘤学和遗传学期刊的广告，网络列表以及在国家会议上发布的引人注目的计划公告，并将其传播给145名医学肿瘤学和60个遗传学计划的董事。每个学员的量身定制的教育计划提供4个联系人的HRS课程，4小时的体验培训，5个小时的跨学科临床会议工作以及每周至少26小时的研究经验/培训。该专业课程包括在第一个项目时期创建和试用的临床癌症遗传学的新研究生课程，并批准了区域大学课程的永久地位。学员学习设计和实施高度跨学科的癌症遗传学和预防研究项目。个人教育计划强调跨学科的课程和会议，并专注于癌症研究项目的成熟以及PHS 398授予建议的准备。学员可以同时通过高级课程工作攻读硕士学位。在第一个资助期，学员的学术生产力非常出色，并导致了8个经过同行评审的出版物。每个学员在专业会议上都介绍了一个或多个摘要。六项培训人员拨款申请已导致校外资金。 CGCDP校友正在继续研究职业轨迹（9名校友中的8名已经担任了学术和/或研究职位，其中一位参与了行业教育），我们正在改善专业课程，引入新的以癌症遗传学为中心的研讨会，并增加了新的研究和跨学科培训元素，并增加了经验丰富的研究，并增加了经验丰富的研究人员。有一个新的访问教授系列，用于概述癌症遗传学研究中的思想领袖和潜在的职业轨迹，以及生物科学和生物信息学方面的新学位学位选择。 CGCDP的成功反映了受训者的生产力和安置，并且在癌症遗传学学科中具有研究专业知识的卫生保健专业人员的持续关键需求。我们的新重点是对上一篇评论推荐的博士后学员，简化了该计划，并将资源集中在最有可能成为癌症遗传学独立研究科学家的学员身上。该计划的毕业生将通过将癌症遗传流行病学转化为个体风险评估工具和可接受的干预措施，从而减轻风险最高的癌症负担。