BIOSTATISTICS CORE

生物统计学核心

• 批准号: 7300577
• 负责人: Steven N. Goodman
• 金额: $ 19.35万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7300577
• 关键词: Area; Arts; Bioinformatics; Biological; Biometry; Biostatistics Core; Books; Breast; Clinical; Clinical Sciences; Clinical Trials; Clinical Trials Design; Collaborations; Collection; Commit; Complex; Consultations; Data; Data Analyses; Data Collection; Data Storage and Retrieval; Detection; Development; Ensure; Equipment; Experimental Designs; Faculty; Fertilization; Funding; Genomics; Head and neck structure; Housing; Human Resources; Imagery; Informatics; Information Storage; K-Series Research Career Programs; Logistics; Manuscripts; Methodology; Modeling; Morphologic artifacts; Phase; Positioning Attribute; Procedures; Publishing; Quality Control; Range; Recording of previous events; Reproduction spores; Research; Research Design; Research Personnel; Resources; Risk Marker; Running; Solutions; Specialist; Techniques; Technology; Testing; Work; Writing; computerized data processing; data acquisition; data management; design; experience; genetic epidemiology; innovation; interest; longitudinal animal study; member; oncology; programs; quality assurance; stem; success; tool

This Core resource will provide comprehensive biostatistics and bioinformatics consultation and collaboration to all projects in the proposed Johns Hopkins Head and Neck SPORE. In addition, it will provide support for data storage, informatics, and computing, and assist with the identification and solution of complex data tasks arising in the course of project activities. Core members will work with project investigators across a wide spectrum of activities, encompassing data acquisition (including study design, feasibility of objectives, availability of public-access genomic information, and data storage), statistical quality control (including artifact detection and preprocessing of data from genomic technologies), data analysis (including visualization, biostatistical modeling, and assistance with manuscript writing), and development of innovative customized biostatistics and bioinformatics methodologies and tools if required by specific projects. The proposed Head and Neck SPORE Biostatistics Core will be housed in the Division of Clinical Trials and Biometry of the Department of Oncology, an active and committed group of biostatistics and bioinformatics faculty members, with access to state-of-the art equipment and a broad range of expertise. This Core resource is the continuation of an existing resource within the original and current Head and Neck SPORE program at Johns Hopkins. Core members have a strong commitment to this SPORE, stemming from: a) a history of collaboration with the investigators of this as well as other SPORE projects, b) an active and independently funded agenda of synergistic projects, and c) a demonstrated interest and understanding of both the biological and analytical questions and challenges. All proposed projects are anticipated to make use of this resource.

该核心资源将提供全面的生物统计学和生物信息学咨询和协作 在拟议的约翰·霍普金斯（John Hopkins）头颈部孢子中的所有项目。此外，它将为 数据存储，信息学和计算，并协助识别和解决复杂数据 在项目活动过程中产生的任务。核心成员将与项目调查员合作 广泛的活动，包括数据获取（包括研究设计，目标的可行性， 公共访问基因组信息和数据存储的可用性），统计质量控制（包括 来自基因组技术的数据的伪影检测和预处理），数据分析（包括 可视化，生物统计建模以及手稿写作的帮助）和创新的发展 定制的生物统计学和生物信息学方法和工具，如果特定项目的要求。这 拟议的头颈孢子生物统计学核心将安置在临床试验的部门中， 肿瘤学系的生物测定法，一组活跃而坚定的生物统计学和生物信息学 教职员工，拥有最先进的设备和广泛的专业知识。这个核心 资源是原始头和颈部孢子中现有资源的延续 约翰·霍普金斯的计划。核心成员对这孢子有坚定的承诺，源于：a）a） 与研究人员以及其他孢子项目合作的历史，b）活跃和 独立资助协同项目的议程，c）对 生物学和分析问题和挑战既是所有提议的项目都预计将做出 使用此资源。