Core A--Administration and Biostatistics Core

核心A——行政和生物统计核心

• 批准号: 7386023
• 负责人: CARLOS M FERRARIO
• 金额: $ 22.27万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7386023
• 关键词: Animals; Biostatistics Core; Computers; Data Analyses; Data Collection; Data Storage and Retrieval; Development; Ensure; Individual; Information Retrieval; Manuscripts; Measures; Methods; Outcome; Phase; Preparation; Principal Investigator; Quality Control; Randomized; Relative (related person); Research; Research Design; Research Personnel; Sample Size; Sampling; Schedule; Scheme; Specific qualifier value; Techniques; Testing; instrument

The biostatistics core's primary objective is to collaborate with investigators in each individual study throughout all phases of their research. We will provide support or be responsible for methodological, statistical and computer related issues including study design, sample size calculation and power analysis, randomization schedules, data collection instruments, data storage and retrieval, data analysis and manuscript preparation. The biostatistics core will be responsible for ensuring that each study design is adequate, including a clear definition of primary and secondary outcomes for each study, according to the hypothesis stated by the principal investigator's sample. There is assistance with sample size determination with specified Type I and Type II errors, provision of alternative methods to test hypothesis when the initial approach is not feasible relative to the pool of animals available and development of randomization schedules or sampling schemes for each study. The Core helps implement quality control measures common to all studies and provides methodological support to each project in developing new analytical techniques as needed and assisting in data analysis and interpretation of results as needed.

生物统计学核心的主要目标是在每项研究的所有阶段与研究人员合作。我们将提供支持或负责方法、统计和计算机相关问题，包括研究设计、样本量计算和功效分析、随机化时间表、数据收集工具、数据存储和检索、数据分析和手稿准备。生物统计学核心将负责确保每项研究设计都是充分的，包括根据主要研究者样本提出的假设，明确定义每项研究的主要和次要结果。协助确定具有指定的 I 型和 II 型误差的样本量，当初始方法相对于可用动物库不可行时提供替代方法来检验假设，以及为每项研究制定随机化时间表或抽样方案。核心帮助实施所有研究通用的质量控制措施，并为每个项目提供方法支持，以根据需要开发新的分析技术，并根据需要协助数据分析和结果解释。