Animal Core

动物核心

• 批准号: 7004378
• 负责人: Francesco John DeMayo
• 金额: $ 8万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-04-01 至 2009-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7004378
• 关键词: animal breeding; animal colony; bioassay; biological models; biomedical facility; embryo /fetus cell /tissue; genetic models; genetically modified animals; laboratory mouse; laboratory rat; model design /development; organ culture; reproduction; tissue /cell preparation

Description (provided by applicant): The overall objective of the Animal Core is to provide center investigators with the ability to utilize animal models in the execution of their proposed research projects, as well as, establish new animal models for the investigation of the mechanisms involved in the regulation of reproduction. The Center for Reproductive Research will utilize two animal models, mice and rats, in the execution of the research projects. Although the use of animal models provides an invaluable source of reagents for investigating regulatory mechanisms in vivo, in a physiologically regulated system, the use of animals in biomedical research is costly with respect to equipment, animal resources and technical expertise. The Animal Core will serve as a resource for the execution and training in the use of all animal manipulations needed in the Center. The Animal Core will minimize the cost of utilizing animal models in the Center Research Program by consolidating the equipment, expertise and animal resources. This will ensure an efficient use of animal research at minimal cost.

描述（由申请人提供）：动物核心的总体目标是提供中心 能够利用动物模型来执行其拟议研究的研究人员 项目，以及建立新的动物模型来研究生殖调节机制。生殖研究中心将利用小鼠和大鼠两种动物模型来执行研究项目。尽管动物模型的使用为研究体内调节机制提供了宝贵的试剂来源，但在生理调节系统中，在生物医学研究中使用动物在设备、动物资源和技术专业知识方面成本高昂。动物核心将作为中心所需的所有动物操作的执行和培训的资源。动物核心将通过整合设备、专业知识和动物资源，最大限度地降低中心研究计划中使用动物模型的成本。这将确保以最低的成本有效利用动物研究。