R01D: An Interdisciplinary Perspective: A Social Science Examination of Oncoferti

R01D：跨学科视角：Oncoferti 的社会科学检验

• 批准号: 7688920
• 负责人: LINDA Leah EMANUEL
• 金额: $ 7.55万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7688920
• 关键词: Adult; Attention; Biological Preservation; Cancer Patient; Child; Childhood; Clinical Trials; Costs and Benefits; Counseling; Cryopreservation; Decision Making; Depth; Economics; Ethnic Origin; Family; Family Physicians; Family member; Fertility; Focus Groups; Gender; Health Personnel; Healthcare; Infertility; Interview; Leadership; Legal; Life; Life Experience; Malignant Neoplasms; Medical; Modeling; Ovarian; Parents; Patients; Physicians; Play; Race; Religion and Spirituality; Reproductive Technology; Research; Role; Scholarship; Science; Social Characteristics; Social Sciences; Socioeconomic Status; Surveys; Technology; Time; Triad Acrylic Resin; Woman; bench to bedside; cancer diagnosis; ethical legal social implication; experience; malignant breast neoplasm; racial and ethnic; social; socioeconomics; survivorship; young adult

The aim of R01D is to advance scholarship at the interface of social and biomedical sciences that will promote and extend our ability to move emerging oncofertility technology from the bench to the bedside. Specifically, to comprehensively examine cancer patients' concerns regarding fertility and how patients, along with their families and physicians, make fertility-related healthcare decisions and to understand the social, legal, and ethical factors that surround those decisions at the time of cancer diagnosis. The proposed research agenda consists of five empirical projects and promotes a triad-model of healthcare decisionmaking whereby the roles of patients, family members (including parents and partners), and healthcare providers will be examined. Moreover, the proposed research agenda utilizes a triangulated methodological approach whereby qualitative and quantitative projects will explore the lived experience of infertility and cancer and will include survey instruments, in-depth interviews, and focus groups; and several projects will integrate mixed methodological approaches within their respective research plan. Project #1, under the direction of Dr. Linda Emanuel, Dr. Laurie Zoloth, and Prof. Dorothy Roberts, will look at the ethical and legal issues surrounding the use of reproductive technologies for cancer patients, with a special emphasis on the implications for pediatric patients and their families. Project #2, under the leadership of Dr. David Dranove, Dr. Andrew Sfekas, and Dr. Charles Bennett, is an economics analysis of how young adult women with cancer weigh the costs and benefits of possible infertility and fertility preservation treatments. Project #3, under the direction of Dr. Kathleen Galvin, Dr. Paul Arnston, and Dr. Maria Chapman, will explore how families facing a child's cancer diagnosis decide whether or not to participate in the ovarian cryopreservation clinical trial and the role that others, such as healthcare practitioners and religious counsel, play in this decision. The aim of this research is to understand how families facing a child's medical crisis make healthcare decisions and to develop a shared decision-making model aimed at informed choice. Project #4, under the direction of Dr. Karrie Snyder, will explore how adult women with breast cancer share their concerns regarding infertility with their physician, how they arrive at treatment decisions, and the impact of possible infertility on their lives and relationships after cancer, with special attention being paid to issues of racial/ethnic and socioeconomic diversity in patient's concerns and survivorship experiences. Project #5, under the direction of Prof. Matthew J. Loscalzo, will be a large-scale survey of cancer patients' concerns and treatment decisions and a comparison of these by key social characteristics including gender, race/ethnicity, socioeconomic status/and family status.

R01D的目的是在社会和生物医学科学的界面上提高奖学金，这将 促进并扩展了我们将新兴的善用技术从长凳转移到床边的能力。 具体而言，要全面研究癌症患者对生育能力以及患者的关注 以及他们的家人和医生，做出与生育有关的医疗保健决定，并了解 癌症诊断时围绕这些决定的社会，法律和道德因素。提议 研究议程由五个实证项目组成，并促进了医疗决策的三合会模型 因此，患者，家庭成员（包括父母和伴侣）和医疗保健的角色 提供者将进行检查。此外，拟议的研究议程利用了三角方法 定性和定量项目将探索不育的生活经验和 癌症，包括调查工具，深入的访谈和焦点小组；几个项目将 将混合的方法论方法整合到其各自的研究计划中。项目＃1，在 Linda Emanuel博士，Laurie Zoloth博士和Dorothy Roberts教授将研究道德和合法 围绕使用生殖技术用于癌症患者的问题，特别强调了 对小儿患者及其家人的影响。在大卫·德拉诺夫（David Dranove）博士的领导下，项目＃2， 安德鲁·斯菲卡斯（Andrew Sfekas）博士和查尔斯·贝内特（Charles Bennett）博士是对年轻妇女的经济学分析 癌症权衡可能不育和生育保存治疗的成本和收益。项目＃3， 在凯瑟琳·加尔文（Kathleen Galvin）博士，保罗·阿恩斯顿（Paul Arnston）和玛丽亚·查普曼（Maria Chapman）博士的指导下，将探讨如何 面对儿童癌症诊断的家庭决定是否参加卵巢冷冻保存 临床试验和其他人（例如医疗保健从业者和宗教顾问）的作用 决定。这项研究的目的是了解面对儿童医疗危机的家庭如何使 医疗保健决策并开发旨在知情选择的共同决策模型。项目＃4， 在Karrie Snyder博士的指导下，将探索成年乳腺癌的成年女性 对医生的不育的担忧，他们如何做出治疗决定以及 癌症后的生活和关系可能不孕，特别注意 在患者的关注和生存经历中，种族/种族和社会经济多样性。项目＃5， 在Matthew J. Loscalzo教授的指导下，将是对癌症患者关注的大规模调查 以及治疗决策以及通过包括性别在内的关键社会特征对这些决定进行比较 种族/种族，社会经济地位/家庭地位。