EFFECTS OF TOM20 AND TOM22 ON THE STRUCTURE OF PROTEINS

TOM20 和 TOM22 对蛋白质结构的影响

• 批准号: 7170965
• 负责人: JOHN R ENGEN
• 金额: $ 5.21万
• 依托单位: NEW MEXICO STATE UNIVERSITY LAS CRUCES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-01 至 2006-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7170965
• 关键词: bioinformatics; education evaluation /planning; educational resource design /development; health science profession; health science research; training; university student

DESCRIPTION (provided by applicant): The New Mexico IDeA Network of Biomedical Research Excellence (NM-INBRE) builds upon the Network established through BRIN funding P20 RR16480 to increase the scope of the Science & Research Core (SRC), initiate a new partnership with the National Center for Genome Resources for bioinformatics training and research, and include a new outreach program for students at other 4-year baccalaureate, tribal and community colleges in the state to increase matriculation in graduate biomedical research programs. The organizational structure of the NM-INBRE includes the research intensive doctoral degree granting institutions: New Mexico State University (NMSU) continuing as the lead, and the University of New Mexico (UNM) providing leadership and direction for the Science and Research Core (SRC). The scientific Partner Institutions include Eastern New Mexico University (ENMU), New Mexico Institute of Mining and Technology (NMT), and New Mexico Highlands University (NMHU). The National Center for Genome Resources, a non-profit institution located in Santa Fe, NM will participate in the bioinformatics initiatives. Programmatic activities, outreach, and funding are coordinated through the Administrative Core (AC). The External Advisory Committee (EAC) provides advice and direction for the research and bioinformatics initiatives. The Steering Committee (SC) establishes and enacts programmatic policies for the operation of the network. Research activities are coordinated through the Science Core. The three thematic research areas include: 1) Structure & Function of Biomolecules thematic area (to understand at the molecular level the mechanisms underlying the functions of proteins that mediate critical cellular processes through detailed knowledge of their structures); 2) Cell and Organism (the elucidation of complex physiological processes, such as hypertension, memory, cell division and oogenesis); 3) Pathogens (builds on existing strengths in infectious disease, immunology, inflammation, and a developing biodefense community).

描述（由申请人提供）：新墨西哥州 IDeA 生物医学研究卓越网络 (NM-INBRE) 建立在通过 BRIN 资助 P20 RR16480 建立的网络基础上，以扩大科学研究核心 (SRC) 的范围，与国家基因组资源中心进行生物信息学培训和研究，并为该州其他四年制学士学位、部落和社区学院的学生提供新的外展计划增加研究生生物医学研究项目的入学率。 NM-INBRE 的组织结构包括研究密集型博士学位授予机构：新墨西哥州立大学 (NMSU) 继续担任牵头机构，新墨西哥大学 (UNM) 为科学研究核心 (SRC) 提供领导和指导）。科学合作机构包括东新墨西哥大学 (ENMU)、新墨西哥矿业技术学院 (NMT) 和新墨西哥高地大学 (NMHU)。位于新墨西哥州圣达菲的非营利机构国家基因组资源中心将参与生物信息学计划。计划活动、外展和资金通过行政核心 (AC) 进行协调。外部咨询委员会 (EAC) 为研究和生物信息学计划提供建议和方向。指导委员会（SC）制定并颁布网络运营的规划政策。研究活动通过科学核心进行协调。三个专题研究领域包括：1）生物分子的结构与功能专题领域（通过详细了解蛋白质的结构，在分子水平上了解介导关键细胞过程的蛋白质功能的机制）； 2）细胞与生物体（阐明复杂的生理过程，如高血压、记忆、细胞分裂和卵子发生）； 3）病原体（建立在传染病、免疫学、炎症和发展中的生物防御社区的现有优势之上）。