Family-centered functional therapy for cerebral palsy

以家庭为中心的脑瘫功能治疗

• 批准号: 6983906
• 负责人: MARY C LAW
• 金额: $ 21.06万
• 依托单位: MCMASTER UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-01 至 2008-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6983906
• 关键词: behavioral /social science research tag; behavioral medicine; cerebral palsy; clinical trials; emotional dependency; family structure /dynamics; functional ability; health care service; human subject; human therapy evaluation; medical rehabilitation related tag; occupational therapy; outcomes research; patient oriented research; physical therapy; preschool child (1-5); quality of life; rehabilitation

DESCRIPTION (provided by applicant): Children with cerebral palsy commonly receive ongoing physical and occupational therapy to facilitate development and to enhance functional independence in movement, self-care, play, school activities and leisure. The primary objective of this project is to conduct a multi-site clinical trial to evaluate the efficacy of a family-centered functional therapy (FCFT) approach in improving performance of functional tasks, mobility, participation in everyday activities, and quality of life in 220 children 12 months to 5 years of age who have cerebral palsy. A randomized clinical trial research design will be used to examine the efficacy of the FCFT approach compared to regular therapy care. 72 therapists (24 in Alberta and 48 in Ontario) will be randomly assigned to provide either FCFT or regular child-focused remediation therapy. Therapists in both groups will receive 3 days of training and expert consultants will be available to support the therapists throughout the study. We will recruit a population-based random sample of 220 children with cerebral palsy ages 12 months to 5 years at recruitment date. After stratification by age and severity, children will receive either FCFT or regular child-focused remediation therapy for a period of 6 months. Outcomes will be evaluated at baseline, after 6 months of treatment and at a 3-month follow-up period. Outcomes will be measured across the domains of the International Classification of Functioning, Disability, and Health including body function and structure (range of motion, spinal alignment), activities (performance of functional tasks, motor function), participation (involvement in formal and informal activities), and environment (parent perceptions of care, parental empowerment). The children's range of motion will also be evaluated by an independent, trained evaluator at baseline, 3, 6, and 9 months to monitor potential adverse effects. We hypothesize that the FCFT approach will significantly improve activity and participation outcomes while leading to no significant decreases in body function and structure outcomes.

描述（由申请人提供）：脑瘫儿童通常接受持续的物理和职业治疗，以促进发育并增强运动、自我护理、游戏、学校活动和休闲方面的功能独立性。该项目的主要目标是进行多中心临床试验，以评估以家庭为中心的功能治疗 (FCFT) 方法在改善 220 年功能任务表现、活动能力、日常活动参与度和生活质量方面的功效。 12 个月至 5 岁的脑瘫儿童。将使用随机临床试验研究设计来检验 FCFT 方法与常规治疗护理相比的疗效。 72 名治疗师（阿尔伯塔省 24 名，安大略省 48 名）将被随机分配以提供 FCFT 或常规以儿童为中心的补救治疗。两组的治疗师都将接受为期 3 天的培训，专家顾问将在整个研究过程中为治疗师提供支持。我们将随机招募 220 名在招募之日年龄为 12 个月至 5 岁的脑瘫儿童作为样本。按年龄和严重程度分层后，儿童将接受 FCFT 或定期以儿童为中心的补救治疗，为期 6 个月。将在基线、治疗 6 个月后以及 3 个月的随访期评估结果。结果将在国际功能、残疾和健康分类的各个领域进行衡量，包括身体功能和结构（运动范围、脊柱排列）、活动（功能任务的执行、运动功能）、参与（参与正式和非正式活动）活动）和环境（父母对照顾的看法、父母的赋权）。受过训练的独立评估员还将在基线、3、6 和 9 个月时对儿童的活动范围进行评估，以监测潜在的不良影响。我们假设 FCFT 方法将显着改善活动和参与结果，同时不会导致身体功能和结构结果显着下降。