Men & Women's Social-Cultural Factors Assoc w/Cervical Cancer Prevention in Panam

男士

• 批准号: 7446126
• 负责人: Anna R. Giuliano
• 金额: $ 3.46万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-15 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7446126
• 关键词: Africa South of the Sahara; Age; American; Antibodies; Antibody Formation; Attitude; Awareness; Behavior; Behavioral; Belief; Brazil; Cancer Burden; Central America; Cervical; Cervical Cancer Screening; Child; Cities; Cluster Analysis; Cognitive; Communities; Country; Data; Development; Device or Instrument Development; Disease; Environmental Risk Factor; Europe; Genital system; Goals; High Prevalence; Hispanics; Household; Human; Human Papilloma Virus Vaccine; Human Papillomavirus; Human papilloma virus infection; Human papillomavirus 16; Human papillomavirus 6; Immigration; Immune response; Immunization; Incidence; Individual; Infection; Infection Control; International; Invasive; Knowledge; Latin America; Life; Male Circumcision; Malignant Neoplasms; Malignant neoplasm of anus; Malignant neoplasm of cervix uteri; Men' s Role; Mexican; Mexico; Molecular; Movement; Natural History; Nature; Not Hispanic or Latino; Oncogenic; Panama; Pap smear; Papillomavirus; Play; Population; Prevalence; Prevention; Process; Prospective Studies; Public Health; Questionnaires; Rate; Relative (related person); Reporting; Research; Research Design; Research Infrastructure; Research Personnel; Risk; Role; Sampling; Screening procedure; Sex Behavior; Sexually Transmitted Diseases; Social Network; Specificity; Techniques; Time; Transportation; Vaccines; Variant; Viral Load result; Woman; base; cervical cancer prevention; cohort; condoms; cost; cross reactivity; experience; male; men; multidisciplinary; non-oncogenic; parent grant; prevent; programs; response; social; social cognitive theory; transmission process; vaccination strategy

DESCRIPTION (provided by applicant): Cervical cancer continues to be an important public health problem in Latin America. Few studies have been conducted in Central America, such as in Panama. The overall goal of the proposed study is to determine HPV and cervical cancer knowledge, attitudes, beliefs, and behaviors as well as community and environmental factors related to Pap smear screening and HPV vaccine acceptability among men and women residing in Panama. The currently proposed FIRCA application will collect information needed to develop and implement prevention and immunization strategies in both men and women living in the San Miguelito district of Panama City with the highest reported prevalence of HPV. Previous studies and preliminary data suggest that the role men play in cervical cancer and HPV transmission, and also in the prevention of the two is often ignored. A community-based participatory process and Social Cognitive Theory will be used to conduct the proposed study. Building-on the infrastructure of the parent grant we propose to develop a community-based advisory board (CAB) comprised of key community leaders in the district of San Miguelito district with highest prevalence of HPV to participate in planning, study design, and instrument development; develop and implement a community-based questionnaire among a random household sample using cluster analysis techniques; assess knowledge of cervical cancer and HPV, and screening awareness and attitudes among men and women, current screening and sexual behaviors among men and women, HPV vaccine acceptability for men, women, and their children; and, understand the social cognitive factors associated with knowledge, attitudes, beliefs, and behaviors toward cervical cancer screening and vaccine acceptability strategies. Rather than focus on structural factors (e.g., access, transportation, cost), we hypothesize that social networks (e.g., men and other women) and norms are important factors that influence screening and sexual behavior among men and women. We also hypothesize that men and women in Panama generally lack knowledge and awareness on HPV and its association with cervical cancer and that men play an important role in women's screening seeking behavior. The proposed study brings together an international multidisciplinary group of researchers to study socio- cultural and behavioral factors associated with cervical cancer prevention and vaccine acceptability. The proposed study will fill this gap by building-on previous experience, current studies, and applying social and behavioral principles in the study of knowledge, attitudes, beliefs and behaviors associated to cervical cancer and HPV control.

描述（由申请人提供）：宫颈癌仍然是拉丁美洲的重要公共卫生问题。在中美洲，例如巴拿马，很少有研究。拟议的研究的总体目标是确定与居住在巴拿马的男性和女性的HPV和宫颈癌知识，态度，信念和行为以及与PAP涂片筛查和HPV疫苗可接受性有关的社区和环境因素。目前提出的FIRCA申请将收集所需的信息，以开发和实施居住在巴拿马城圣米格利托区男性和女性的预防和免疫策略，其据报道最高的HPV患病率。先前的研究和初步数据表明，男性在宫颈癌和HPV传播中的作用以及预防两者的作用通常被忽略。基于社区的参与过程和社会认知理论将用于进行拟议的研究。在建立父母赠款基础设施的基础设施上，我们建议建立一个基于社区的顾问委员会（CAB），该咨询委员会（CAB）由圣米格利托地区的主要社区领导者组成，HPV的患病率最高，以参与计划，研究设计和仪器开发；使用聚类分析技术在随机家庭样本中开发和实施基于社区的问卷；评估宫颈癌和HPV的知识，以及筛查男性和女人之间的意识和态度，男性和女人的当前筛查和性行为，男女的HPV疫苗可接受性；并且，了解与知识，态度，信念和对宫颈癌筛查和疫苗可接受性策略相关的社会认知因素。我们假设社交网络（例如男人和其他妇女）和规范不是影响男性和女性筛查和性行为的重要因素，而不是专注于结构因素（例如，访问，运输，成本）。我们还假设巴拿马的男人和女性通常缺乏对HPV及其与宫颈癌的联系的知识和认识，男性在妇女筛查寻求行为中起着重要作用。拟议的研究汇集了一个国际多学科研究人员小组，以研究与宫颈癌预防和疫苗可接受性相关的社会文化和行为因素。拟议的研究将通过建立以前的经验，当前的研究以及在与宫颈癌和HPV控制相关的知识，态度，信念和行为的研究中运用社会和行为原则来填补这一空白。