Molecular Surgeon Symposium on Genetics and Genomics of Pancreatic Cancer

分子外科医生胰腺癌遗传学和基因组学研讨会

• 批准号: 7408620
• 负责人: Changyi Chen
• 金额: $ 0.5万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7408620
• 关键词: Award; Clinical; Data; Diagnosis; Discipline; Funding; Future; Gene Expression Alteration; Gene Expression Regulation; General Population; Genetic; Genomics; Goals; Housing; Institution; Journals; Malignant neoplasm of pancreas; Manuscripts; Medical Students; Medical center; Medicine; Molecular; Mucins; Neuropilins; Operative Surgical Procedures; Participant; Pathogenesis; Physicians; Postdoctoral Fellow; Publications; RAS genes; Request for Applications; Research; Research Personnel; Scientific Advances and Accomplishments; Scientist; Series; Students; Surgeon; Texas; Time; Travel; abstracting; anticancer research; college; concept; cost; day; interest; member; mesothelin; mouse model; posters; symposium

DESCRIPTION (provided by applicant): This R13 application requests funds to partially (50%) support the Molecular Surgeon Symposium on Genetics and Genomics of Pancreatic Cancer, which will be the fourth time of the Molecular Surgeon Symposium series in the Baylor College of Medicine (BCM). The symposium will be held at the Texas Medical Center, Houston, Texas, on April 12 and 13, 2008. The overall goal of this interdisciplinary scientific symposium is to bring together scientists and physicians from diverse fields with a common interest in understanding Genetics and Genomics of Pancreatic Cancer. It will also provide a unique opportunity for trainees (postdoctoral fellows, clinical residents and fellows, medical students, and other scientists) to interact with investigators in the field of cancer research. This symposium is unique in that it will provide a forum for presenting and discussing the latest advances in pancreatic cancer research. This one and a half day symposium will consist of an opening keynote presentation with the following scientific sessions: 1). Genomic alterations in pancreatic cancer; 2). Gene expression alteration in pancreatic cancer; 3). Gene regulation and functions in pancreatic cancer-I (mouse model and k-ras gene); and 4). Gene regulation and functions in pancreatic cancer-II (Smad, XIST, CACAM6, mucin, mesothelin, SSTR, neuropilins, and PDX-1). In addition, poster session will be organized. Attendees will be invited to submit an abstract to poster section planned for the symposium that will allow all attendees, especially students, residents, and young investigators, to present their data and fully participate in discussions. We anticipate approximately 250 attendees. The limited attendance, focused scientific sessions, and highly successful poster session combined will provide an exciting forum for the exchange of ideas and will provide extensive opportunities for participation by a diverse group of scientists interested in pancreatic cancer. Funding is requested for planning and organizing the meeting and for travel and housing costs for speakers and those trainees selected for travel awards. Matching funds (50%) will be provided by the Institution to cover other costs. The Organizing/Scientific Committee will consist of members from research disciplines that represent the integrated/educational concept of the Symposium. At the conclusion of the symposium, participants should be able to: 1) understand the impact and opportunities of genetics and genomics on pancreatic cancer research; 2) discuss recent scientific advances related to molecular pathogenesis, diagnosis, and therapy for pancreatic cancer; 3) determine the future directions of pancreatic cancer research; and 4) establish a collaborative network in pancreatic cancer research. All presentations will be video-taped and presented on the "The Molecular Surgeon" website for general public access (website has been established since 1999). Furthermore, invited speakers are encouraged to submit manuscripts related to their presentations to "World Journal of Surgery" for consideration of publications.

描述（由申请人提供）：该R13申请要求部分资金（50％）支持胰腺癌遗传学和基因组学的分子外科医生研讨会，这将是贝勒医学院（BCM）中分子外科医生研讨会系列的第四次。 该研讨会将于2008年4月12日至13日在德克萨斯州休斯敦的德克萨斯医学中心举行。该跨学科科学研讨会的总体目标是将来自不同领域的科学家和医生汇集在一起​​，这些科学家和医生在了解胰腺癌的遗传学和基因组学方面具有共同的兴趣。 它还将为学员（博士后研究员，临床居民和研究员，医学生和其他科学家）提供一个独特的机会，可以与癌症研究领域的研究人员进行互动。 该研讨会的独特之处在于它将提供一个论坛，用于介绍和讨论胰腺癌研究的最新进展。 这个为期一个半天的研讨会将包括一个开放的主题演讲，其中包括以下科学会议：1）。胰腺癌的基因组改变； 2）。胰腺癌的基因表达改变； 3）。胰腺癌I（小鼠模型和K-RAS基因）中的基因调节和功能；和4）。胰腺癌-II的基因调节和功能（Smad，Xist，Cacam6，粘蛋白，间皮素，SSTR，Neuropilins和PDX-1）。 此外，将组织海报会议。 将邀请与会者向计划的研讨会提交摘要，以允许所有与会者，尤其是学生，居民和年轻调查人员提供他们的数据并充分参加讨论。 我们预计约有250名与会者。 有限的出席人士，专注的科学会议和非常成功的海报会议的结合将为思想交流提供一个令人兴奋的论坛，并将为一群对胰腺癌感兴趣的科学家提供广泛的参与机会。 要求资金计划和组织会议，以及演讲者的旅行和住房费用以及被选为旅行奖的受训者。 机构将提供匹配资金（50％），以支付其他费用。 组织/科学委员会将由来自研究学科的成员组成，这些成员代表了研讨会的综合/教育概念。 研讨会结束时，参与者应能够：1）了解遗传学和基因组学对胰腺癌研究的影响和机会； 2）讨论与分子发病机理，诊断和胰腺癌治疗有关的最新科学进步； 3）确定胰腺癌研究的未来方向； 4）在胰腺癌研究中建立协作网络。 所有演示文稿将在“分子外科医生”网站上进行视频划分，并在用于通用公共访问的网站上（自1999年以来就建立了网站）。 此外，鼓励受邀的发言人将与其演讲有关的手稿提交给“世界手术杂志”以考虑出版物。

项目成果

Improved diagnosis of pancreatic adenocarcinoma using haptoglobin and serum amyloid A in a panel screen.

• DOI: 10.1007/s00268-008-9853-9
• 发表时间: 2009-04
• 期刊: WORLD JOURNAL OF SURGERY
• 影响因子: 2.6
• 作者: Firpo, Matthew A.;Gay, David Z.;Granger, Steven R.;Scaife, Courtney L.;DiSario, James A.;Boucher, Kenneth M.;Mulvihill, Sean J.
• 通讯作者: Mulvihill, Sean J.

Profiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysis.

• DOI: 10.1007/s00268-008-9833-0
• 发表时间: 2009-04
• 期刊: WORLD JOURNAL OF SURGERY
• 影响因子: 2.6
• 作者: Zhang, Yuqing;Li, Min;Wang, Hao;Fisher, William E.;Lin, Peter H.;Yao, Qizhi;Chen, Changyi
• 通讯作者: Chen, Changyi

MicroRNAs: control and loss of control in human physiology and disease.

• DOI: 10.1007/s00268-008-9836-x
• 发表时间: 2009-04
• 期刊: WORLD JOURNAL OF SURGERY
• 影响因子: 2.6
• 作者: Li, Min;Marin-Muller, Christian;Bharadwaj, Uddalak;Chow, Kwong-Hon;Yao, Qizhi;Chen, Changyi
• 通讯作者: Chen, Changyi

Current understanding and potential immunotherapy for HIV-associated squamous cell carcinoma of the anus (SCCA).

• DOI: 10.1007/s00268-008-9835-y
• 发表时间: 2009-04
• 期刊: WORLD JOURNAL OF SURGERY
• 影响因子: 2.6
• 作者: Marin-Muller, Christian;Li, Min;Chen, Changyi;Yao, Qizhi
• 通讯作者: Yao, Qizhi