14th Biennial FASEB Summer Research Conference on Retinoids

第 14 届 FASEB 类视黄醇双年度夏季研究会议

基本信息

批准号：
7479974
负责人：
SUSAN M. SMITH
金额：
$ 3万
依托单位：
FEDERATION OF AMER SOC FOR EXPER BIOLOGY
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-04-01 至 2009-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7479974
关键词：
Address American Biology Cells Collaborations Computer Retrieval of Information on Scientific Projects Database Databases Development Diabetes Mellitus Discipline Disease Embryonic Development Functional disorder Funding Goals Grant Health Homeostasis Human Immunity Immunologist International Investigation Knowledge Learning Malignant Neoplasms Metabolism Molecular Nutritional Physiological Physiology Play Postdoctoral Fellow Process Range Regulation Request for Applications Research Research Activity Research Personnel Retinoid Receptor Retinoids Role Scientist Senior Scientist Societies Stem cells Structure Students Therapeutic Time Tretinoin United States National Institutes of Health Vision Vitamin A Work career cell growth regulation cell type disorder prevention insight lectures obesity risk posters prevent research and development skin disorder symposium

项目摘要

DESCRIPTION (provided by applicant): This application requests partial support for the 14th Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference on Retinoids to be held at the Omni New Haven at Yale Hotel in New Haven, CT from June 15-20, 2008. This bi-annual research conference has been very well attended (ranging from 125 to 200 attendees over the past 24 years) and remains the sole major national and international conference that addresses the full spectrum of retinoid biology. Knowledge of the importance of retinoids to a diverse group of biologically and medically important processes has increased very rapidly over the last two decades. Nevertheless, there is much that still needs to be learned regarding retinoid actions in both normal human physiology and pathophysiology. To meet this need for information, there is a great deal of ongoing research activity focused on the retinoids (the NIH CRISP database indicates that there are currently 191 funded NIH grants involving retinoid biology). The 2008 conference will consist of a plenary lecture, platform presentations and poster sessions that will allow for the exchange of new research findings amongst scientific attendees. The main topics to be addressed at the conference include: (1) retinoid metabolism and homeostasis; (2) structure and regulation of retinoid receptors; (3) enzymatic control of retinoic acid action; (4) retinoids in vision; (5) retinoids in cancer; (6) physiological actions of retinoids; (7) retinoids in development; (8) retinoid regulation of cell growth and differentiation; and (9) retinoid regulation of stem cell plasticity and differentiation. The overall goal of the proposed conference on retinoids is to bring together a group of investigators (including senior scientists, mid-career scientists, junior scientists, postdoctoral fellows, and graduate students) who work in diverse disciplines (as biochemists, molecular biologists, nutritional scientists, cancer researchers, developmental biologists, vision researchers, cell biologists, immunologists, chemists, and clinicians) to present and discuss their newest research findings that share a common focus on the retinoids. This conference will provide a forum for the critical review of recent research and for the development of new research ideas and collaborations. This will stimulate new investigations that in time will provide needed insight into the essential actions of retinoids in preventing disease and maintaining good health. Retinoids, the active forms of vitamin A, have wide ranging effects on many aspects of human health including vision, embryonic development, immunity, and the differentiation of diverse cell types; they are important therapeutics for cancer and skin disorders, and may play a role in diabetes/obesity risk and certain ocular diseases. This bi-annual research conference provides the sole major national and international forum that addresses the full spectrum of retinoid biology. Its goal is to stimulate scientific exchange and new investigations that will provide needed insights into retinoid roles in disease prevention and treatment.

描述（由申请人提供）：该申请要求对第14届美国实验生物学联合会（FASEB）夏季研究会议在2008年6月15日至20日在康涅狄格州纽黑文市Yale Haven举行的视网膜夏季研究会议。这次两年一次的研究会议都非常愉快（在过去的24年中，整个会议都在全国性的会议上，以及SOLE的整个会议，并确定了SOLE的整个会议。生物学。在过去的二十年中，视网膜类似对多样化的生物学和医学重要过程的重要性的了解已经非常迅速。然而，在正常的人类生理学和病理生理学中，仍然需要学习很多关于类维生素类动作的知识。为了满足对信息的需求，有很多持续的研究活动集中在类视网膜上（NIH CRISP数据库表明目前有191名资助的NIH赠款涉及视网膜类似生物学）。 2008年的会议将包括全体演讲，平台演示和海报会议，该会议将允许在科学与会者中交换新的研究结果。会议上要解决的主要主题包括：（1）类维生素性代谢和稳态；（2）类维生素性受体的结构和调节；（3）视黄酸作用的酶控控制；（4）视力符合视力；（5）癌症中的类视黄素；（6）类维生素类似的生理作用；（7）开发的类视黄素；（8）细胞生长和分化的类维生素性调节；（9）类维生素的干细胞可塑性和分化。 The overall goal of the proposed conference on retinoids is to bring together a group of investigators (including senior scientists, mid-career scientists, junior scientists, postdoctoral fellows, and graduate students) who work in diverse disciplines (as biochemists, molecular biologists, nutritional scientists, cancer researchers, developmental biologists, vision researchers, cell biologists, immunologists, chemists, and clinicians) to present and讨论他们最新的研究结果，这些发现共同关注类维生素类似。这次会议将为对最新研究的批判性审查以及新的研究思想和合作的发展提供论坛。这将刺激新的调查，即及时将提供必要的洞察力，以了解性类维生素类动物在预防疾病和保持身体健康方面的基本作用。维生素A的活性形式的视网膜类动物对人类健康的许多方面都有广泛的影响，包括视觉，胚胎发育，免疫力以及各种细胞类型的分化；它们是针对癌症和皮肤疾病的重要治疗方法，并且可能在糖尿病/肥胖风险和某些眼部疾病中发挥作用。这次两年一次的研究会议提供了唯一的主要国家和国际论坛，该论坛涉及类视网膜生物学的全部范围。它的目标是刺激科学交流和新的研究，这些研究将为您在预防疾病和治疗中的类视黄素角色提供所需的见解。