2008 Chromatin Structure and Function Gordon Research Conference

2008年染色质结构与功能戈登研究会议

• 批准号: 7406546
• 负责人: ROBERT KINGSTON
• 金额: $ 2万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7406546
• 关键词: Area; Basic Science; Chromatin; Chromatin Structure; Clinical Trials; Collaborations; Communication; Communities; Complex; Development; Europe; Fostering; Funding; Genome; Health; Human; International; Malignant Neoplasms; Methodology; Numbers; Pathway interactions; Play; Regulation; Relative (related person); Research; Research Personnel; Role; Scientist; Series; Structure; System; Translational Research; United States; career; concept; developmental disease; interest; programs; success; symposium

DESCRIPTION (provided by applicant): This proposal seeks to obtain partial funding for the 21st Gordon Research Conference (GRC) entitled "Chromatin Structure and Function." Since its inception in 1972, the "Chromatin" GRC has played a central role in establishing and maintaining communication and collaboration among the diverse group of scientists with a vital interest in chromatin. The conference seeks to advance our understanding of the role of chromatin structure in the functioning of genomes. This is a fast evolving research area with increasing relevance for human health, notably cancer and developmental disorders. The focus of the meeting, chromatin and its role in regulation, has evolved into a topic that connects the very basic sciences to translational research including clinical trials. The prime aim of the conference is to foster the transatlantic communication between researchers by facilitating an international and interdisciplinary exchange of information, ideas, concepts and methodology. The Chromatin GRC has an excellent track record of catalysing a large number of fruitful interactions between researchers in the United States and others elsewhere in the world, particularly in Europe, where a very strong chromatin community has also been established. The second important aim of the conference is to enhance the potential of scientists early in their careers. The conference series remains one of the most popular GRCs, more than two-fold oversubscribed with an increase in applications of 50% in the year 2006 relative to 2004. The success of the meeting is due to the fact that the field is still expanding and exciting discoveries are being made each year, which are reflected by a program that features the most recent developments. The upcoming conference will put special emphasis on describing chromatin as a complex system of structures that are involved in fine-tuning the functioning of the eukaryotic genome and its the programming and reprogramming along pathways of proliferation and differentiation.

描述（由申请人提供）：本提案旨在为题为“染色质结构与功能”的第 21 届戈登研究会议 (GRC) 获得部分资金。 自 1972 年成立以来，“染色质”GRC 在对染色质有着重大兴趣的不同科学家群体之间建立和维持沟通与合作方面发挥了核心作用。 该会议旨在增进我们对染色质结构在基因组功能中的作用的理解。 这是一个快速发展的研究领域，与人类健康，特别是癌症和发育障碍的相关性越来越大。 会议的焦点是染色质及其在调控中的作用，已经发展成为一个将基础科学与包括临床试验在内的转化研究联系起来的主题。 会议的主要目的是通过促进国际和跨学科的信息、思想、概念和方法的交流来促进研究人员之间的跨大西洋交流。 染色质 GRC 在促进美国和世界其他地方的研究人员之间进行大量富有成效的互动方面有着出色的记录，特别是在欧洲，那里也已经建立了非常强大的染色质社区。 会议的第二个重要目标是增强科学家职业生涯早期的潜力。 该会议系列仍然是最受欢迎的 GRC 之一，2006 年的申请量比 2004 年增加了两倍多，申请量增加了 50%。会议的成功归功于该领域仍在不断扩大和每年都会有令人兴奋的发现，这些发现反映在以最新发展为特色的计划中。 即将举行的会议将特别强调将染色质描述为一个复杂的结构系统，该系统参与微调真核基因组的功能及其沿着增殖和分化途径的编程和重编程。