ACS Symposium, Frontiers in Chemical Toxicology

ACS 研讨会，化学毒理学前沿

• 批准号: 7540635
• 负责人: Michael P Stone
• 金额: $ 0.8万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7540635
• 关键词: American; Applications Grants; Area; Base Excision Repairs; Chemicals; Communities; Cytochrome P450; DNA Damage; Discipline; Enzyme Inhibition; Epigenetic Process; Funding; Future; Growth; Nucleotide Excision Repair; Numbers; Pennsylvania; Pharmaceutical Preparations; Philadelphia; Research; Role; Safety; Science; Scientist; Series; Societies; Structure; Title; Toxicology; frontier; nanotoxicity; programs; repaired; structural biology; symposium; technique development

DESCRIPTION (provided by applicant) This grant application requests funding for partial support of a series of symposia with the title "Frontiers in Chemical Toxicology". These symposia are part of the program to be presented by the American Chemical Society Division of Chemical Toxicology at the 236th National Meeting and Exposition of the Society in Philadelphia, Pennsylvania on August 17 through 21, 2008. These symposia will provide forums for the presentation of emerging research in key areas of chemical toxicology, including 1) the structural biology of DNA damage as related to repair, with emphasis on base excision repair and nucleotide excision repair, 2) the role of epigenetics in chemical toxicology, 3) emerging issues of nanotoxicity, 4) cytochrome P450 structure, function, and mechanism, and 5) drug safety prediction as related to cytochrome P450 enzyme inhibition and induction, to the chemical community. The contribution of the chemical community to the development of techniques in this arena has increased greatly in recent years, with future growth only limited by lack of cross-talk between the large numbers of disciplines involved in this area of the biomedical sciences, hence the need for this symposium. Highly respected scientists from a variety of disciplines have agreed to present their most recent findings.

描述（由申请人提供） 该赠款申请要求为一系列专题讨论会提供资金，标题为“化学毒理学领域”。这些座谈会是该计划的一部分，由美国化学学会化学毒理学部在2008年8月17日至21日在宾夕法尼亚州费城举行的第236届全国会议和该协会的博览会上展示。这些ISPOSIA将为excionology and Incecomologicy and Iscraption and Iscraption of 1）提供的论坛提供论坛。核苷酸切除修复，2）表观遗传学在化学毒理学中的作用，3）纳米毒性的新出现问题，4）细胞色素P450的结构，功能和机制，以及5）与细胞色素P450酶抑制和诱导相关的药物安全预测。 近年来，化学界对该领域技术发展的贡献大大增加，只有未来的增长仅受生物医学科学领域涉及的大量学科之间缺乏串扰的限制，因此需要该研讨会。 来自各个学科的备受推崇的科学家已同意提出他们的最新发现。