Exploitation of Advanced Photonic Boisensors(EAPho-Bio- A new tool for fast and untrasensitive detection of biochemical and biomolecular interactions

先进光子生物传感器的开发（EAPho-Bio-一种快速、非灵敏检测生化和生物分子相互作用的新工具

• 批准号: EP/D500427/1
• 负责人: Lin Zhang
• 金额: $ 12.85万
• 依托单位: Aston University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2006
• 资助国家: 英国
• 起止时间: 2006 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FD500427%2F1
• 关键词: Exploitation; Advanced; Photonic; Boisensors; EAPho

This programme proposes to carry out novel research on the exploitation of a new class of photonic biosensors for fast, sensitive and real-time detection of very small biochemical samples and the dynamic analysis of protein/protein, protein/DNA and cellular interactions. The photonic biosensors will be developed using UV and femtosecond inscribed microstructures in speciality fibres, sensitised by post-inscription processing and bioactivated using bioactive affinity techniques. It is envisaged that, when developed, the highly bio-sensitive/selective optical sensors will have potential applications in genomics, proteomics and drug discovery research and development, as well as in environmental monitoring.The proposed programme intends making to form a strong interaction between the photonics technology and lifescience applications by carrying out this project collaboratively between the Photonics Research Group and Molecular Bioscience Research Group at Aston University.L. Beneficiaries

该计划建议对新型光子生物传感器开发进行新的研究，以快速，敏感和实时检测非常小的生化样品以及蛋白质/蛋白质/DNA和细胞相互作用的动态分析。光子生物传感器将使用特种纤维中的紫外线和飞秒刻有微观结构开发，并通过刻画后处理敏感并使用生物活性亲和力技术进行生物活化。可以预见的是，高度生物敏感/选择性的光学传感器将在基因组学，蛋白质组学和药物发现研究和开发以及环境监测中具有潜在的应用。拟议的计划旨在在PhoteScience技术和生物研究小组之间进行研究小组和分类研究小组之间的研究，以形成强大的相互作用。受益人

项目成果

Numerical and Experimental Analysis of Sensitivity-Enhanced RI Sensor Based on Ex-TFG in Thin Cladding Fiber

• DOI: 10.1109/jlt.2015.2422076
• 发表时间: 2015-07-15
• 期刊: JOURNAL OF LIGHTWAVE TECHNOLOGY
• 影响因子: 4.7
• 作者: Yan, Zhijun;Sun, Zhongyuan;Zhang, Lin
• 通讯作者: Zhang, Lin

EDC-mediated oligonucleotide immobilization on a long period grating optical biosensor

• DOI: 10.4172/2155-6210.1000173
• 发表时间: 2015-01-01
• 期刊: J. Biosens. Bioelectron
• 作者: Chen, X.;Liu, C.;Zhang, L.
• 通讯作者: Zhang, L.