Biostatistics and Computational Biology

生物统计学和计算生物学

• 批准号: 7314843
• 负责人: MEREDITH M REGAN
• 金额: $ 32.52万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7314843
• 关键词: ALPP; Animals; Area; Biometry; Biostatistics Core; Cancer Center; Clinical; Clinical Research; Collaborations; Communities; Computational Biology; Computer software; Consult; Consultations; Correlative Study; Country; Dana-Farber Cancer Institute; Data; Data Analyses; Data Collection; Databases; Development; Ensure; Epidemiologic Studies; Genomics; Growth; Human Resources; Institutes; Laboratories; Leadership; Malignant neoplasm of prostate; Massachusetts; Medical; Medicine; Outcome; Public Health Schools; Reporting; Reproduction spores; Research; Research Activity; Research Design; Research Personnel; Standards of Weights and Measures; Technology; Translational Research; anticancer research; career; data integrity; data management; design; programs; quality assurance; statistics

The Biostatistics and Computational Biology Core will join and expand the existing Biostatistics Core and computational aspects of the existing Genomics Core of the current DF/HCC Prostate Cancer SPORE in one Core under the leadership of the Core Director, Dr. Meredith Regan, and Co-Director, Dr. Pablo Tamayo. The new integrated Biostatistics and Computational Biology Core reflects the growth of computational, data- intensive approaches to cancer research at cancer centers around the country. The Core personnel will draw from expertise at the Dana-Farber Cancer Institute (DFCI), the Harvard School of Public Health (HSPH), and the Broad Institute, a research collaboration of the Massachusetts Institute of Technology (MIT) and Harvard academic and medical communities that focuses on genomic medicine. The DF/HCC Prostate Cancer SPORE Biostatistics and Computational Biology Core will provide consultation and collaboration on all research activities within the SPORE, including Projects, Developmental Projects, Projects of the Career Development Awardees, and the other SPORE Cores to ensure the highest standards of scientific rigor in all areas, including study design, data management and integrity, and data analysis and interpretation. The specific aims are to: 1. Provide biostatistical and computational biology expertise for the planning and design, conduct, analysis, and reporting of laboratory, genomic, animal, translational, clinical (including associated correlative studies), and epidemiological studies for SPORE projects, Developmental Projects, Projects of the Career Development Awardees, and other SPORE Cores. 2. Provide consultation on data collection, storage and quality assurance, statistics, and computational biology software and programs and coordination of laboratory results with parameters and outcomes from clinical studies or clinical/translational research databases. 3. Provide short-term biostatistics and computational biology consulting to the entire group of SPORE researchers.

生物统计学和计算生物学核心将加入并扩展现有的生物统计学核心和 当前DF/HCC前列腺癌孢子的现有基因组核心的计算方面 核心主任梅雷迪思·里根（Meredith Regan）博士和联合导演帕勃罗·塔玛约（Pablo Tamayo）的领导下。 新的综合生物统计学和计算生物学核心反映了计算，数据的增长 全国各地癌症中心的癌症研究的密集方法。核心人员将画 从达纳 - 法伯癌症研究所（DFCI），哈佛公共卫生学院（HSPH）和 马萨诸塞州技术研究所（MIT）和哈佛大学的研究合作 专注于基因组医学的学术和医学界。 DF/HCC前列腺癌孢子生物统计学和计算生物学核心将提供咨询 以及在孢子中的所有研究活动中的合作，包括项目，发展项目， 职业发展获奖者和其他孢子核心的项目，以确保最高标准 各个领域的科学严谨性，包括研究设计，数据管理和完整性以及数据分析以及 解释。 具体目的是： 1。提供生物统计和计算生物学专业知识，用于计划和设计，行为， 分析和报告实验室，基因组，动物，翻译，临床的报告（包括相关 相关研究）和孢子项目，发展项目的流行病学研究， 职业发展获奖者和其他孢子核心的项目。 2。提供有关数据收集，存储和质量保证，统计和计算的咨询 生物学软件和程序以及与参数和结果的实验​​室结果协调 来自临床研究或临床/转化研究数据库。 3。向整个孢子提供短期生物统计学和计算生物学咨询 研究人员。