Construction/SEBLAB/Regional Biocontainment Laboratory

建筑/SEBLAB/区域生物防护实验室

• 批准号: 7212514
• 负责人: Richard Banfield Marchase
• 金额: $ 300万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7212514
• 关键词: Construction; SEBLAB; Regional; Biocontainment; Laboratory

DESCRIPTION (provided by applicant): The University of Alabama at Birmingham (UAB) proposes to construct on its campus the Southeast Biocontainment Laboratory Alabama Birmingham (SEBLAB). This 41,060 gsf Regional Biocontainment Laboratory (RBL) will require $15.9 million of NIAID funding to be matched with $5.3 million from UAB. UAB is one of six institutions leading the Southeastern Regional Center for Excellence in Emerging Infections and Biodefense, the focus of biodefense efforts for the eight-state Region IV. UAB is an outstanding choice for an RBL for several reasons. These include the experience and complementary biodefense capabilities of UAB's affiliate, Southern Research Institute, the national leadership role that the UAB Center for Disaster Preparedness has taken in biodefense planning and training, and exceptional core facilities. Most importantly, UAB investigators have distinguished records in virology, bacterial pathogenesis, immunology, and vaccine development. Many of these investigators, as well as new recruits, are now bringing their skills to bear on issues directly relevant to biodefense and emerging infections, concentrating on NIAID priority pathogens. This effort is now limited by the availability of biocontainment space on the UAB campus. SEBLAB will greatly facilitate maximal national benefit from this talent, and will provide a rich environment for visiting researchers from other institutions doing research that requires biocontainment. SEBLAB's design includes flexible and secure BSL-2 and 3 laboratories, ABSL-3 housing and procedure space, and offices. In the event of a bioterrorism emergency, SEBLAB will provide surge capacity for diagnostics and other necessary analyses to enhance state and regional public health responses.

描述（由申请人提供）：伯明翰（UAB）的阿拉巴马大学提议在其校园内建造东南生物卫生实验室阿拉巴马州伯明翰（Seblab）。这项41,060个GSF区域生物疗养实验室（RBL）将需要1590万美元的NIAID资金与UAB的530万美元相匹配。 UAB是领导东南部新兴感染和生物融合卓越区域卓越区域中心的六个机构之一，这是对八邦IV的生物防御努力的重点。由于多种原因，UAB是RBL的绝佳选择。其中包括UAB分支机构，南方研究所的经验和互补的生物化能力，UAB灾难准备中心在BiodeFense计划和培训中扮演的国家领导角色以及出色的核心设施。最重要的是，UAB研究人员在病毒学，细菌发病机理，免疫学和疫苗发育方面具有区分记录。这些调查人员中的许多以及新的新兵现在都将他们的技能带入与生物反应和新兴感染直接相关的问题，重点关注NIAID优先病原体。现在，这项工作受到UAB校园中生物疗养空间的可用性的限制。 Seblab将极大地促进这一人才的最大国家利益，并将为来自其他机构的研究人员提供丰富的环境，从事需要生物培养的研究。 Seblab的设计包括灵活且安全的BSL-2和3个实验室，Absl-3住房和程序空间以及办公室。如果发生生物恐怖主义，Seblab将为诊断和其他必要分析提供激增能力，以增强州和区域公共卫生的反应。