Early Life Influences on Elderly Health in the Developing World

早期生活对发展中国家老年人健康的影响

• 批准号: 7477737
• 负责人: MARY C MCENIRY
• 金额: $ 14.76万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7477737
• 关键词: Adult; Africa; African; Aging; American; Asia; Asians; Bangladesh; Benchmarking; Birth; Businesses; Caribbean natives; Caribbean region; Characteristics; Childhood; China; Chronic; Chronic Disease; Condition; Costa Rica; Country; Data; Demography; Developed Countries; Developing Countries; Development; Diabetes Mellitus; Diet; Disease; Doctor of Philosophy; Economics; Education; Elderly; Engineering; Epidemiology; Evolution; Exposure to; Finches; Future; Ghana; Goals; HGS gene; Health; Health Status; Health Transition; Healthcare; Heart Diseases; Height; Income; India; Individual; Indonesia; Inequality; Intervention; Keratectomy, Subepithelial, Laser-Assisted; Knee; Latin America; Learning; Life; Life Style; Living Standards; Mentors; Mexico; Morbidity - disease rate; Mortality Decline; Multivariate Analysis; Nature; Obesity; Outcome; Patient Self-Report; Population; Principal Investigator; Procedures; Public Health; Puerto Rico; Relative (related person); Reporting; Research; Research Personnel; Risk; Seasons; Smoking; Social Security; Socioeconomic Status; Speed; Stimulus; Surface; System; Taiwan; Testing; Time; Work; career; disability; drinking; early childhood; experience; frailty; mortality; socioeconomics

DESCRIPTION (provided by applicant): Differences in the evolution of mortality in the developing world during the 20th century will have important implications for elderly health status for at least the next 20 to 30 years. Due to the particular nature of mortality decline in the developing world, we hypothesize that early life conditions have important effects on later adult health in these countries and that the effects are more salient in some types of demographic regimes than in others. The proposed research assesses the relation between early childhood conditions and adult morbidity and mortality among different demographic regimes in Latin American and Caribbean (LAC), Asian and African elderly populations, using as benchmarks data from relevant industrialized elderly populations such as the US, UK and Taiwan. The research builds upon preliminary results obtained among the LAC elderly. Continuing with this work, we test guiding hypotheses using comparable cross national and panel data in health outcomes (self-reported health, functional limitations, obesity, chronic conditions such as diabetes and heart disease, and mortality), early childhood conditions (height, knee height, month of birth, SES during childhood, childhood health), adult SES (income, education) and adult lifestyle (smoking, diet, drinking). We use multivariate analyses to examine health profiles, determinants of health status and individual health transitions. We also incorporate procedures such as vignettes to adjust for under (over) reporting of health; try new estimation procedures for the over (under) reporting of health conditions and procedures to adjust for differential survival in chronic diseases; and use Waaler-type surfaces to estimate expected relative mortality risk. This 5-year K25 project provides support for a PhD industrial engineer to make a successful career transition from applied public and business sectors to future independent research in health demography among aging populations in the developing world and/or in cross-cultural U.S. settings. K25 provides the stimulus to meet the candidate's specific aims in career development: (1) learn from the extensive experience of a committee of seasoned mentors from UW-Madison's CDE/CDHA in health demography and economics in aging populations through timely cross-national research; (2) augment competency in advanced quantitative health demography and epidemiology through formalized study.

描述（由申请人提供）：至少在接下来的20至30年中，在20世纪，发展中国家死亡率演变的差异将对老年人健康状况具有重要意义。由于发展中国家死亡率下降的特殊性质，我们假设早期生活条件对这些国家的后来成人健康具有重要影响，并且在某些类型的人口统计方面的影响比在某些类型的人口统计方面更为显着。拟议的研究评估了拉丁美洲和加勒比海（LAC），亚洲和非洲老年人群的不同人口统计制度之间的幼儿条件与成人发病率与死亡率之间的关系，并将其用作来自美国，英国和台湾等相关工业化老年人群的基准测试数据。该研究基于LAC老年人获得的初步结果。 Continuing with this work, we test guiding hypotheses using comparable cross national and panel data in health outcomes (self-reported health, functional limitations, obesity, chronic conditions such as diabetes and heart disease, and mortality), early childhood conditions (height, knee height, month of birth, SES during childhood, childhood health), adult SES (income, education) and adult lifestyle (smoking, diet, drinking).我们使用多元分析来检查健康状况，健康状况的决定因素和个人健康转变。我们还结合了诸如小插曲之类的程序，以调整（过度）健康报告；尝试对健康状况和程序过度报告的新估计程序，以适应慢性疾病的差异生存；并使用WAALER型表面来估计预期的相对死亡率风险。这个为期5年的K25项目为博士工业工程师提供了支持，从而成功地从应用公共和商业领域过渡到发展中国家和/或美国跨文化环境中老龄化人口的未来独立研究。 K25提供了实现候选人在职业发展方面的具体目标的刺激：（1）从UW-Madison的CDE/CDHA经验丰富的导师委员会的广泛经验中学习，通过及时的跨国研究，在老年人人口中，在衰老中的健康人口统计学和经济学方面学习； （2）通过正式研究增强高级定量健康人口统计学和流行病学的能力。