Harvard Planning Grant for Institutional Clinical and Translational Science Award

哈佛机构临床和转化科学规划拨款

• 批准号: 7215029
• 负责人: DANIEL EDWIN SINGER
• 金额: $ 25.43万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-17 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7215029
• 关键词: NIH Roadmap Initiative tag; administrative personnel; biomedical facility; biomedical resource; career; clinical research; education evaluation /planning; health science research analysis /evaluation; health services research tag; information dissemination; medical education; training

DESCRIPTION (provided by applicant): We are submitting an application for a Planning Grant for an Institutional Clinical and Translational Science Award (CTSA) from the Harvard Medical School (HMS) and Harvard-affiliated Academic Health Centers (AHCs). Harvard is committed to establishing an academic home for clinical research, the Harvard Clinical and Translational Science Center (CISC), that will integrate resources across Harvard, facilitate productive interdisciplinary collaborations, foster successful career development through Roadmap T32 and K12Programs, link investigators with experts in potentially transformative technologies, such as genomics, advanced imaging, and bioengineering, provide pilot grant support for promising, interdisciplinary research, and generally speed translation of scientific insights into beneficial clinical care. In this proposal we describe our vision for the CISC, and a planning process to establish its governance, administration, content, and evaluation. Harvard's research resources, faculty, and trainees are extraordinary but frequently dispersed and isolated. Our CTSC will seek to integrate clinical research across Harvard to add new dimensions of research productivity benefiting patients. In the process we will integrate and realign our four separate General Clinical Research Centers. Informatics will reinforce the CTSC's links across disciplines and institutions. The magnitude of this task dictates that we start with a planning grant. We have constituted an Executive Committee composed of Harvard's leaders in clinical research and outlined subcommittees to address each of the critical components of the program. We will assemble an inventory of relevant resources and seek expert advice from within and outside Harvard. An organizational consultant will help us identify programmatic synergies and obstacles and help assure the planning process meets its milestones. The Principal Investigator is both an accomplished clinical investigator and an Associate Dean with a long history of success working across Harvard's institutional boundaries. The Trustees include the AHC CEOs and Chief Academic Officers as well as HMS Deans. These Trustees reflect broad institutional commitment to the Program and the authority to direct institutional change and investments of space and money to underwrite the Program. We believe our planning process is specific, innovative yet disciplined, and should be robust. A full and competitive CTSA application will be produced in a timely manner.

描述（由申请人提供）：我们正在向哈佛医学院 (HMS) 和哈佛附属学术健康中心 (AHC) 提交机构临床和转化科学奖 (CTSA) 规划拨款申请。哈佛致力于建立临床研究的学术家园，即哈佛临床和转化科学中心 (CISC)，该中心将整合哈佛的资源，促进富有成效的跨学科合作，通过路线图 T32 和 K12 项目促进成功的职业发展，将研究人员与专家联系起来。潜在的变革性技术，如基因组学、先进成像和生物工程，为有前景的跨学科研究提供试点拨款支持，并总体上加速将科学见解转化为有益的临床护理。在本提案中，我们描述了 CISC 的愿景，以及建立其治理、管理、内容和评估的规划流程。哈佛大学的研究资源、教职员工和实习生都非常出色，但经常分散和孤立。我们的 CTSC 将寻求整合哈佛大学的临床研究，以增加新的研究生产力，造福患者。在此过程中，我们将整合和重新调整我们的四个独立的综合临床研究中心。信息学将加强 CTSC 跨学科和机构的联系。这项任务的规模决定了我们从规划拨款开始。我们成立了一个由哈佛大学临床研究领域的领导者组成的执行委员会，并设立了几个小组委员会来解决该计划的每个关键组成部分。我们将整理相关资源清单，并寻求哈佛内外的专家建议。组织顾问将帮助我们识别计划协同作用和障碍，并帮助确保规划过程达到其里程碑。首席研究员既是一位卓有成就的临床研究员，又是一位副院长，在哈佛各个机构的边界上有着悠久的成功经验。受托人包括 AHC 首席执行官和首席学术官以及 HMS 院长。这些受托人反映了对该计划的广泛机构承诺以及指导机构变革以及空间和资金投资以承保该计划的权力。我们相信，我们的规划过程具体、创新、有纪律，而且应该是稳健的。将及时制作完整且有竞争力的 CTSA 申请。