THE F-MARS STUDY

F-火星研究

• 批准号: 7381015
• 负责人: REBECCA DIN-DZIETHAM
• 金额: $ 9.77万
• 依托单位: MOREHOUSE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-08-01 至 2007-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381015
• 关键词: MARS; STUDY; MARS; STUDY

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This pilot study develops instruments needed to assess environmental factors (diet, physical activity and stress) and genetic factors (family history of cardiovascular disease and a few genes that regulate vessel flexibility) that may impact on vascular function. Their reproducibility and validity are assessed in the context of three-generation African-American families. The hypertensive set includes the proband, i.e., the person with hypertension who serves as index person to recruit his/her family, the proband¿s spouse, offspring aged eight or more, first degree relatives, and parents. A control person, i.e, normotensive, is matched by age and gender to the hypertensive proband and his/her 3-generation family recruited to form the normotensive. The participants are seen once except for the members of the core family (proband, spouse and offspring) who come a second time to the clinic for repeat vascular exam

该主题是使用NIH/NCRR资助的中心赠款提供的资源的众多研究主题之一。主题和研究人员（PI）可能已经从另一名NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构是针对该中心的，这不是调查人员的机构。该试点研究开发工具需要评估环境因素（饮食，体育锻炼和压力）和遗传因素（心血管疾病的家族史以及一些调节血管柔韧性的基因）可能会影响血管功能。它们的可重复性和有效性是在三代非裔美国人家庭的背景下评估的。高血压套件包括探险，即有高血压的人，他是索引人，招募了他/她的家人，概率尊敬的人，八岁以上的后代，一级亲戚和父母。一个对照人，即正常人，与性别和性别相匹配，与高血压概率以及他/她的三代家庭招募以形成正常的人。除了第二次去诊所进行重复血管检查的核心家族（概率，配偶和后代）之外，参与者曾经看到过一次