General Clinical Research Center

全科临床研究中心

• 批准号: 7014231
• 负责人: A LORRIS BETZ
• 金额: $ 271.33万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-06 至 2011-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7014231
• 关键词: clinical research; human subject

EXCEED THE SPACE PROVIDED. This competing renewal application requests continued support for the General Cinical Research Center (GCRC) at the University of Utah which has operated continuously since 1964. The GCRC supports both adult and pediatric clinical research protocols at a discrete inpatient and outpatient unit at the University of Utah Health Sciences Center, Primary Childrens Medical Center (connected to University Hospital by a bridge) and the Huntsman Cancer Institute (connected to University Hospital by a tunnel). The GCRC provides facilities and staff for investigations of hospitalized and ambulatory patients that require skilled intensive nursing care, precise specimen collection and processing, rigorous dietary control, and expert laboratory, bioinformatics and biostatistical support. Qualified faculty members study clinical conditions that span the major fields of clinical investigation with an emphasis on the inherited basis of human disease. The GCRC also fosters the training of young clinical investigators through an NIH funded clinical research training program (K30) and through an NIH funded summer medical student research training program (T35). We request support for 1,215 "A" inpatient days and 4,562 "A" outpatient visits annually and 24.9 core FTE positions distributed among 36 individuals including 10.5 FTE registered nurses and the staffs of the Administrative Core, the Core Laboratory, Bionutrition Research Unit, and the Informatics and Biostatistical Cores. This funding also supports .6 FTE of the Research Subjects Advocate Program that places the protection of human subjects at the forefront of all research undertaken by the GCRC. Major research activities proposed in this grant include the following areas of human physiology and disease: hereditary colon cancer syndromes, hereditary neurodegenerative disorders, hereditary disorders of iron and heme metabolism, hereditary psychiatric disorders, hypereosinophilic syndromes, diabetes and heart disease.

超过空间 假如。 这种竞争性更新申请要求继续为一般电影研究中心提供支持 （GCRC）在犹他大学以来一直在不断运作的犹他大学。GCRC支持两者 成人和小儿临床研究方案，在大学的住院和门诊单位 犹他州健康科学中心，初级儿童医学中心（通过 桥梁）和亨斯曼癌症研究所（通过隧道连接到大学医院）。 GCRC 提供设施和人员，以调查住院和门诊的患者，需要熟练 密集护理，精确的标本收集和加工，严格的饮食控制和专家 实验室，生物信息学和生物统计支持。合格的教职员工研究临床状况 跨越临床研究的主要领域，重点是人类疾病的遗传基础。这 GCRC还通过NIH资助的临床研究来培养年轻临床研究者的培训 培训计划（K30）以及通过NIH资助的夏季医学学生研究培训计划 （T35）。 我们要求支持1,215“ A”住院日和4,562“ A”门诊访问和24.9核心FTE 在36个人中分配的职位，包括10.5 fte注册护士和 行政核心，核心实验室，Bionutrition研究部门以及信息学和生物统计学 内核。这项资金还支持0.6 FTE研究主题倡导计划，该计划将 保护人类受试者在GCRC进行的所有研究的最前沿。主要研究 本赠款中提出的活动包括以下人类生理学和疾病的领域：遗传 结肠癌综合征，遗传神经退行性疾病，铁和血红素的遗传疾病 代谢，遗传性精神疾病，嗜酸性综合征，糖尿病和心脏病。