SLEEP IN CHILDREN WITH JUVENILE RHEUMATOID ARTHRITIS

患有幼年类风湿性关节炎的儿童的睡眠

• 批准号: 7379408
• 负责人: CAROL A LANDIS
• 金额: $ 2.23万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7379408
• 关键词: SLEEP; CHILDREN; JUVENILE; RHEUMATOID; ARTHRITIS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Juvenile rheumatoid arthritis (JRA), the most prevalent form of arthritis in childhood, is a disease of unknown etiology, and its course is variable and characterized by episodic remissions and exacerbations. Recent findings suggest that sleep is disrupted in children with JRA. Sleep disturbances in this vulnerable population include difficulty falling asleep, staying asleep, early morning awakening, and excessive daytime sleepiness. At present, we do not know the severity of disturbed sleep in children with JRA, nor do we understand how much disturbed sleep contributes to daytime sleepiness, fatigue, and impaired performance. Our recent longitudinal study of sleep patterns in children with JRA suggests that sleep disturbances are more likely to occur during periods of arthritic flare. Sleep quality may be an important predictor of how children experience symptoms of the disease, but this has not been reported, or is simply unknown. The purpose of this study is to assess sleep, daytime sleepiness, performance and symptom experience in children with JRA during a week of arthritic flare or during a week of remission. Findings from this study will provide the foundation for designing subsequent intervention studies to enhance the quality of sleep in children living with chronic pain

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。少年类风湿关节炎（JRA）是儿童期最普遍的关节炎形式，是一种病因未知的疾病，其病程是可变的，并以情节性的缓解和加剧的疾病为特征。 最近的发现表明，JRA儿童的睡眠破坏了。这种脆弱人群中的睡眠障碍包括难以入睡，睡着，清晨觉醒和白天过度嗜睡。目前，我们不知道患有JRA的儿童睡眠的严重程度，也不知道睡眠有多大的睡眠有助于白天的嗜睡，疲劳和表现受损。我们最近对JRA儿童睡眠模式的纵向研究表明，在关节炎时期，睡眠障碍更有可能发生。睡眠质量可能是儿童如何经历这种疾病症状的重要预测指标，但这尚未报告，或者根本未知。这项研究的目的是评估在关节炎的一周或缓解一周内，JRA儿童的睡眠，白天的嗜睡，表现和症状经历。这项研究的结果将为设计随后的干预研究提供基础，以增强慢性疼痛儿童的睡眠质量