BEHAVIOR TREATMENT AND NUTRITION IN PEDIATRIC CHRONIC DISEASE

儿科慢性病的行为治疗和营养

• 批准号: 7374494
• 负责人: LORI J STARK
• 金额: $ 2.42万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7374494
• 关键词: BEHAVIOR; TREATMENT; NUTRITION; PEDIATRIC; CHRONIC

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Children and adolescents with inflammatory bowel disease (IBD; ulcerative colitis and Crohn's Disease) are at risk for low bone mass and fracture in early adulthood. The present project compares a Behavior Intervention Program (BI) to a standard of care condition (STC) for increasing dietary calcium intake and bone mass in children with IBD. The program evaluates calcium intake pre to post intervention (approximately 8 weeks later) and at 6 month intervals over 2 years. Bone mass will also be examined at baseline and at 6 month intervals for 2 years post treatment. It is hypothesized that children with IBD receiving the BI will have a significantly greater dietary calcium intake per day than children with IBD receiving STC pre to post treatment (8 weeks). It is also hypothesized that the increased calcium intake of the BI group will be maintained across 24 months post treatment and that the calcium intake of the BI group will be significantly greater than the STC group. Finally, it is hypothesized that the BI condition will result in a significantly greater increase in bone mass than the STC.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。患有炎症性肠病（IBD；溃疡性结肠炎和克罗恩病）的儿童和青少年在成年初期有低骨量和骨折的风险。本项目将行为干预计划（BI）与IBD儿童饮食中钙摄入量和骨骼量增加的护理条件（STC）进行了比较。该计划评估干预后（大约8周后）和2年间间隔6个月的钙摄入量。骨骼质量还将在基线和6个月间隔进行治疗后2年进行检查。假设患有IBD接受BI的儿童每天的饮食钙摄入量要比IBD接受STC之前的儿童的饮食摄入量明显高（8周）。还可以假设，在治疗后24个月内将维持BI组的钙摄入量的增加，并且BI组的钙摄入量将显着大于STC组。最后，假设BI条件将导致骨骼质量明显大于STC。