INSULIN RESISTANCE AND ENDOTHELIAL CELL FUNCTION IN MORBID OBESITY

病态肥胖中的胰岛素抵抗和内皮细胞功能

• 批准号: 7375373
• 负责人: MARGARET A. MCNURLAN
• 金额: $ 1.43万
• 依托单位: STATE UNIVERSITY NEW YORK STONY BROOK
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-12-01 至 2006-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7375373
• 关键词: INSULIN; RESISTANCE; ENDOTHELIAL; CELL; FUNCTION

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research is to understand why some obese individuals become resistant to the hormone insulin; that is, they are in a pre-diabetic state while other obese individuals are not. We are going to measure the degree of insulin and then relate that to a number of different metabolic markers. We think that the markers will be higher in individuals who are insulin resistant. This will help us to understand the nature of insulin resistance.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。这项研究的目的是了解为什么有些肥胖个体对激素胰岛素有抵抗力。也就是说，他们处于糖尿病前状态，而其他肥胖个体则不处于糖尿病状态。我们将测量胰岛素的程度，然后将其与许多不同的代谢标记联系起来。我们认为，耐胰岛素的个体中的标记将更高。这将有助于我们了解胰岛素抵抗的性质。