Therapeutic Massage for Generalized Anxiety Disorder

广泛性焦虑症的治疗性按摩

• 批准号: 7103981
• 负责人: KAREN J SHERMAN
• 金额: $ 27.3万
• 依托单位: KAISER FOUNDATION HEALTH PLAN OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7103981
• 关键词: anxiety; anxiety disorders; clinical research; experimental designs; quality of life; stress

DESCRIPTION (provided by applicant): Anxiety and stress are common and costly problems afflicting American adults and are a leading reason for using complementary and alternative medical (CAM) therapies. Although massage is one of the most popular CAM treatments for anxiety, its effectiveness has never been rigorously evaluated for a diagnosed anxiety disorder. This study lays the groundwork for a full-scale randomized clinical trial to evaluate the effectiveness, safety, and costs of massage for generalized anxiety disorder (GAD), a common and frustrating condition that often presents with many somatic symptoms, including muscle tension. In Phase I of this project, we will develop and pre-test key components of such a trial, including participant selection criteria and the treatment protocols for the massage and comparison groups. In Phase II, we will use the components developed during Phase I to conduct a pilot trial evaluating the effectiveness and safety of massage for GAD. We will randomize 75 persons with GAD to therapeutic massage (n=25) or to one of two control groups ("thermotherapy" or a "relaxing environment"; n=25 for each). We will evaluate the effect of massage on anxiety-related symptoms and dysfunction, quality of life, and costs of GAD-related provider visits by comparing changes in these outcomes in the massage and control groups at the end of treatment and at 6 months. The pilot study will permit us to identify and address unanticipated problems with the study design, outcome measures, and treatment protocols; to estimate the samples sizes needed for an adequately-powered full-scale trial and the related recruitment period that would be required; and to obtain preliminary estimates of the effectiveness and safety of massage for GAD. At the conclusion of this project, we will be well positioned to prepare a competitive grant proposal for a full-scale trial evaluating the effectiveness of massage as a treatment for persons with GAD. RELEVANCE: Although Americans commonly visit massage therapists for anxiety and stress , no studies have evaluated massage as a treatment for a diagnosed anxiety disorder. By first developing a series of massage treatments for generalized anxiety disorder and then evaluating these treatments in a pilot study, this study represents the first step toward filling this important gap in our knowledge.

描述（由申请人提供）：焦虑和压力是困扰美国成年人的常见且代价高昂的问题，也是使用补充和替代医学 (CAM) 疗法的主要原因。尽管按摩是最流行的焦虑症 CAM 治疗方法之一，但其有效性从未针对确诊的焦虑症进行过严格评估。这项研究为全面随机临床试验奠定了基础，该试验旨在评估按摩治疗广泛性焦虑症 (GAD) 的有效性、安全性和费用。GAD 是一种常见且令人沮丧的疾病，通常会出现许多躯体症状，包括肌肉紧张。在该项目的第一阶段，我们将开发并预先测试此类试验的关键组成部分，包括参与者选择标准以及按摩组和对照组的治疗方案。在第二阶段，我们将使用第一阶段开发的组件进行试点试验，评估按摩治疗广泛性焦虑症的有效性和安全性。我们将 75 名广泛性焦虑症 (GAD) 患者随机分配到按摩治疗组 (n=25) 或两个对照组之一（“热疗”或“放松环境”；每组 n=25）。我们将通过比较按摩组和对照组在治疗结束时和 6 个月时这些结果的变化，评估按摩对焦虑相关症状和功能障碍、生活质量以及与 GAD 相关的就诊费用的影响。试点研究将使我们能够识别并解决研究设计、结果测量和治疗方案方面的意外问题；估计充分动力的全面试验所需的样本量以及所需的相关招募期；并获得按摩治疗广泛性焦虑症的有效性和安全性的初步估计。在该项目结束时，我们将能够为评估按摩治疗广泛性焦虑症患者的有效性的全面试验准备一份竞争性拨款提案。相关性：尽管美国人经常因焦虑和压力而去看按摩治疗师，但没有研究评估按摩作为诊断焦虑症的治疗方法。通过首先开发一系列针对广泛性焦虑症的按摩疗法，然后在试点研究中评估这些疗法，这项研究代表了填补我们知识中这一重要空白的第一步。