CERT Coordinating Center

CERT 协调中心

• 批准号: 7332922
• 负责人: MARK CHRISTOPHER HORNBROOK
• 金额: $ 39.97万
• 依托单位: KAISER FOUNDATION RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7332922
• 关键词: CERT; Coordinating; Center

DESCRIPTION (Provided by the Applicant): This proposal supports the application from The Center for Health Research (TCHR), Kaiser Permanente under RFA HS-07-0008 to serve as the Coordinating Center (CC) for the Centers for Education and Research on Therapeutics (CERTs) Program (U18) sponsored by the Agency for Healthcare Research and Quality (AHRQ). The CERTs are a national demonstration program conducting research and education programs that advance the optimal use of drugs, biologicals, and medical devices. The CERTs program is organized as a network of 11 research centers, each focusing on a broad therapeutic theme. In general, themes represent areas where limited comparative information exists on the risks, benefits, and interactions of newer and older therapeutic agents. The CERTs intend to bring together all the stakeholders in the process of discovering, testing, marketing, prescribing, consuming, and evaluating therapeutics. Working from the organizational context of evidence-driven, capitated, population-based medicine, KP offers an important policy counterbalance to fee-for-service academic medicine. The CERTs' research agenda is also clearly focused on translational science. We will leverage our position as a Clinical and Translational Science Awards center and a member of numerous research networks to establish important relationships among researchers across the country. This proposal represents a private-public consortium among Kaiser Permanente (an internationally renowned, non-profit, integrated healthcare delivery system and CERTs partner), the Oregon Health & Science University (a major academic biomedical research and health center, as well as, in partnership with TCHR, one of the first 12 NIH Clinical and Translational Science Awards), the AHRQ, the Food and Drug Administration (FDA), and the CERTs Steering Committee (SC) to support the third cycle of the CERTs' research and educational programs. Given that the CERTs SC is the primary decision-making body, and the CC's role is to support and enhance the SC's functioning and coordination among the CERTs with respect to research, education, and fund-raising, the specific aims of our proposed CC are four-fold: 1) Provide a seamless transition from the previous CERTs CC at Duke University Medical Center to the TCHR CERTs CC to ensure that all ongoing and planned SC initiatives and CERTs research and educational activities are not adversely affected; 2) Provide infrastructure and leadership support to the CERTs SC in carrying out the overall mission of conducting research and providing education that will advance the optimal use of drugs, medical devices, and biological products; 3) Develop the CERTs strategic plan and tactical priorities for the next 4-year funding cycle; and 4) Conduct evaluations of the CERTs program to identify the extent to which the strategic goals have been attained, the implications of these successes, and barriers encountered and overcome.

描述（由申请人提供）：该提案支持卫生研究中心（TCHR），Kaiser Permanente的申请，根据RFA HS-07-0008，作为医疗研究和质量研究和质量研究机构赞助的医疗机构（U18）计划的教育和研究中心的协调中心（CC）。证书是一项国家示范计划，开展了研究和教育计划，旨在推动药物，生物学和医疗设备的最佳使用。 CERTS计划是由11个研究中心组成的网络，每个网络都集中在广泛的治疗主题上。通常，主题代表了有关较新的和老式治疗剂的风险，益处和相互作用的比较信息有限的领域。证书打算在发现，测试，营销，处方，消费和评估治疗学的过程中将所有利益相关者汇集在一起​​。 KP是在循证驱动，投票式，基于人群的医学的组织背景下工作的，这为服务为服务的学术医学提供了重要的政策抵消。证书的研究议程也显然专注于转化科学。我们将利用我们作为临床和转化科学奖中心的地位，以及众多研究网络的成员，以在全国各地的研究人员之间建立重要的关系。 This proposal represents a private-public consortium among Kaiser Permanente (an internationally renowned, non-profit, integrated healthcare delivery system and CERTs partner), the Oregon Health & Science University (a major academic biomedical research and health center, as well as, in partnership with TCHR, one of the first 12 NIH Clinical and Translational Science Awards), the AHRQ, the Food and Drug Administration (FDA), and the证书指导委员会（SC）支持证书研究和教育计划的第三个周期。鉴于Certs SC是主要决策机构，而CC的作用是支持和增强SC在研究，教育和筹款方面的证书之间的功能和协调性，我们提议的CC的具体目的是四倍：1）提供了从杜克大学医学中心和TCH CC CC的无缝过渡，以确保duke University Cent and SCC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CC CON均可提供。活动不会受到不利影响； 2）为CERTS SC提供基础设施和领导力支持，以执行进行研究并提供教育的整体使命，以推动最佳使用药物，医疗设备和生物产品； 3）在下一个4年筹资周期中制定证书的战略计划和战术优先事项； 4）对证书计划进行评估，以确定实现战略目标的程度，这些成功的含义以及遇到和克服的障碍。