2005 CELL BIOLOGY OF METALS GORDON CONFERENCE

2005 金属细胞生物学戈登会议

• 批准号: 6932650
• 负责人: Dennis R. Winge
• 金额: $ 0.8万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-15 至 2006-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6932650
• 关键词: cell biology; copper; iron; meeting /conference /symposium; metal metabolism; travel; zinc

DESCRIPTION (provided by applicant): The principal objective of the 2005 Cell Biology of Metals Gordon Conference is to inaugurate a new Gordon Conference on this rapidly expanding sub-discipline. The first meeting will bring together scientists, ranging from established investigators to graduate students, to present and discuss the most recent advances in cell physiology of copper, iron and zinc ions in eukaryotic systems. The questions encompassed by cell biology of metals are how do cells achieve metal ion homeostasis and how do cells specifically sense diverse metal ions in these mechanisms? Ultimately, such systems facilitate the correct metals locating to the approximately one-third of proteins that require metal-cofactors for folding or catalysis. Sessions will deal with metal ion homeostasis in the central nervous system, intertissue regulation of metal ion homeostasis, transport of metal ions and metal ion complexes, intracellular trafficking of metal ions, metal ion signaling and global analyses of metals in cells. An important goal is to address the interconnections that exist in homeostatic mechanisms of different metal ions. The meeting aims to draw together the investigators and trainees carrying out research on the mentioned topics in attempt to promote communication, collaborations and share advances in methodologies. The novelty of the Cell Biology of Metals conference lies in the unique focus on cell biological issues related to metal ions and the integrated consideration of multiple metal ions that are essential to life.

描述（由申请人提供）： 2005 年金属细胞生物学戈登会议的主要目标是就这一快速发展的子学科发起一个新的戈登会议。第一次会议将汇集从资深研究人员到研究生的科学家，介绍和讨论真核系统中铜、铁和锌离子的细胞生理学的最新进展。金属细胞生物学所涉及的问题是细胞如何实现金属离子稳态以及细胞如何在这些机制中特异性地感知不同的金属离子？最终，此类系统有助于将正确的金属定位到大约三分之一需要金属辅助因子进行折叠或催化的蛋白质。会议将讨论中枢神经系统中的金属离子稳态、金属离子稳态的组织间调节、金属离子和金属离子复合物的运输、金属离子的细胞内运输、金属离子信号传导和细胞中金属的整体分析。一个重要的目标是解决不同金属离子稳态机制中存在的相互联系。会议旨在聚集对上述主题进行研究的研究者和学员，以促进沟通、合作并分享方法论的进展。金属细胞生物学会议的新颖之处在于对与金属离子相关的细胞生物学问题的独特关注以及对生命必需的多种金属离子的综合考虑。