Low-Cost Device for Digital Retinal Imaging

用于数字视网膜成像的低成本设备

• 批准号: 7440842
• 负责人: ANN E ELSNER
• 金额: $ 37.36万
• 依托单位: TRUSTEES OF INDIANA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-05 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7440842
• 关键词: Anterior; Area; Blindness; Blood Vessels; Caring; Cataract; Complications of Diabetes Mellitus; Contracts; Crowding; Cyst; Cystoid Macular Edema; Databases; Detection; Devices; Diabetes Mellitus; Diabetic Retinopathy; Early Diagnosis; Electronics; Elements; Engineering; Exudate; Eye; Fiber; Fundus; Goals; Hemorrhage; Hybrids; Image; Imagery; Imaging Device; Imaging Techniques; Invasive; Iris; Laboratories; Lasers; Light; Lighting; Methods; Microaneurysm; Minority; Miosis disorder; Morphologic artifacts; Mydriatics; Ophthalmoscopes; Optics; Outcome; Pathway interactions; Patients; Photography; Price; Production; Provider; Pupil; Quality Control; Range; Reading; Resolution; Retina; Retinal; Retinal Detachment; Risk; Rural; Scanning; Screening procedure; Series; Signal Transduction; Source; Specialist; Standards of Weights and Measures; System; Techniques; Testing; Time; Traction; Variant; Work; blind; cost; design; detector; diabetic; diabetic cataract; digital; health disparity; improved; instrument; light scattering; macula; macular edema; neovascularization; novel strategies; polarimetry; prototype; sensor; voltage

We plan to optimize a low cost, simple-to use, non-invasive imaging device, the Laser Scanning Digital Camera (LSDC). The LSDC has laser scanning illumination to increase contrast over a fundus camera and will have the user interface of a consumer-level digital camera. The LSDC serves as a screening device that provides image storage and a database for store and forward use by eye care providers. It is non-mydriatic and comfortable for patients. We will use the longest wavelength that provides acceptable contrast between 532 and 850 nm, thereby minimizing problems due to dark fundi and cataract. Our goal is for the LSDC to have an up front, one-time cost < 10% of high end imaging devices, but sensitivity of identifying patients at risk is the main criterion. We will investigate the key features for early detection with grading, plus the more advanced ones likely in the rural and urban underserved. Along with microaneurysms and hemhorrages, we will investigate macular edema including cystoid macular edema; retinal vascular changes and neovascularization; hard exudates; visualization through diabetic cataract; macular traction; retinal detachment; and iris neovascularization. We plan 5 Specific Aims: 1) build a prototype LSDC that images 40 deg of retina, 2) perform laboratory tests with a high end laser scanning device to determine if a comfortable, near IR light source can produce acceptable image quality instead of the typical uncomformably bright shorter wavelegnths that constrict the pupil, 3) explore what sensitvities and contrasts are achieved in pathological features using near IR imaging techniques, 4) optimize the optical design and wavelength selection of the LSDC, and 5) perform a blind grading study with prototype LSDC in the laboratory. Our goal is to reduce health disparities and the resulting loss of vision due to diabetic retinopathy. We are developing a method of screening for diabetic retinopathy that is far more comfortable than present nonmydriatic cameras that use bright light. The aim is to make an instrument that works like a consumer digital camera. Both of these factors may help reach more patients. We will investigate the key features considered necessary for early detection grading, and also more the serious damage that is typically discovered late in the rural and urban underserved.

我们计划优化低成本，易于使用，非侵入性成像设备，激光扫描数字 相机（LSDC）。 LSDC具有激光扫描照明，以增加对眼镜摄像头的对比度和 将具有消费级数码相机的用户界面。 LSDC用作筛选设备 提供图像存储和一个数据库，用于商店和眼部护理提供商的前瞻性使用。它是非杂草的 适合患者。我们将使用最长的波长，在之间提供可接受的对比度 532和850 nm，从而最大程度地减少了由于黑暗基金会和白内障而引起的问题。我们的目标是让LSDC 具有前面的一次性成本<占高端成像设备的10％，但要识别患者的敏感性 风险是主要标准。 我们将调查用评分提早检测的关键功能，以及更先进的功能 农村和城市服务不足。除了微型尿布和血管外，我们还将研究黄斑 水肿，包括囊状黄斑水肿；视网膜血管变化和新血管形成；硬渗出； 通过糖尿病性白内障可视化；黄斑牵引；视网膜脱离；和虹膜新血管形成。 我们计划5个特定目的：1）构建图像40度视网膜的原型LSDC，2）执行实验室 使用高端激光扫描设备进行测试，以确定舒适的红外光源是否可以产生 可接受的图像质量，而不是典型的不易理解的明亮的较短的浪潮，从而收缩 学生，3）探索使用近红外成像的病理特征在病理特征中实现了哪些敏感性和对比度 技术，4）优化LSDC的光学设计和波长选择，5） 实验室中使用原型LSDC的原型进行分级研究。 我们的目标是减少健康差异和由于糖尿病性视网膜病变而导致的视力丧失。我们 正在开发一种筛查糖尿病性视网膜病的方法，该方法比目前的非乳皮病更舒适 使用明亮的光的摄像机。目的是制造一种像消费者数字一样工作的乐器 相机。这两个因素都可能有助于吸引更多的患者。我们将研究关键功能 被认为是早期检测分级所必需的，也是更多的严重损害 在农村和城市贫乏的后期发现。