Adolescent Medicine Trials Network for HIV/AIDS Interve*

艾滋病毒/艾滋病干预青少年医学试验网络*

• 批准号: 7195770
• 负责人: MARVIN E BELZER
• 金额: $ 66.98万
• 依托单位: CHILDREN'S HOSPITAL OF LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-16 至 2011-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7195770
• 关键词: AIDS/HIV problem; Address; Adherence; Adolescent; Adolescent Medicine; Adolescent Medicine Trials Network; Area; Behavioral; Caring; Case Management; Cellular Phone; Clinical; Clinical Trials; Communities; Community Trial; Compassion; County; Data Quality; Development; Geographic Locations; HIV; Health; Health Services Research; Health education; Healthcare; Hospitals; Intervention; Interview; Los Angeles; Love; Medical; Medical Education; Mental Health; Mission; Modeling; Pediatric Hospitals; Population; Pregnancy; Prevention; Preventive; Process; Production; Protocols documentation; Public Health; Research; Research Infrastructure; Research Training; Resources; Risk; Services; Site; Site Visit; Substance abuse problem; Surveys; Therapeutic; Therapy Clinical Trials; United States; Youth; base; child well being; experience; indexing; innovation; multidisciplinary; performance site; planetary Atmosphere; programs; response; tertiary prevention; violence prevention

DESCRIPTION (provided by applicant): The mission of Children's Hospital Los Angeles (CHLA) is "to advance the health and well-being of children and adolescents by integrating medical care, preventive services, medical education, and research in response to the needs of our community and in an atmosphere of love, compassion, and respect for people. "Since the early 1980's, the Division of Adolescent Medicine at CHLA has focused on reducing risks for young people through innovative models of service, research and training established in partnership with the community. Through these programs, the Division provides health care, mental health, case management, health education, and substance abuse treatment services to over 9000 youth annually, and is involved in community-level interventions for pregnancy, HIV, and violence prevention. Since the inception of the Adolescent Trials Network (ATM), CHLA has established itself as a productive Adolescent Medicine Trials Unit (ATU), contributing to the primary mission of the ATUs in the recruitment and retention of subjects in clinical trials and production of high quality data. In the area of behavioral trials, CHLA has far greater participation and recruitment than any other ATM site. For community prevention trials (Connect to Protect(r)), CHLA is one of the first three (of fifteen) sites to complete the index interviews and begin the brief venue based surveys. As for therapeutic trials, CHLA has consistently been in the top third for recruitment. The quality of our site management is reflected in consistently positive reviews at our semi-annual site visits. The Los Angeles ATU has not only established itself as a productive ATU, but has contributed to the ATM through active involvement in committees and the development of new behavioral protocols. The site PI has been the ATU chair for all five years of this project and served on the Executive and Site performance committees. In addition, CHLA is one of the few ATU sites to have initiated an ATN protocol (ATN 039). CHLA is currently in the process of developing yet another original protocol involving the use of cell phones as reminders to address non-adherence. The following application documents that Children's Hospital Los Angeles (CHLA), Division of Adolescent Medicine has the experience, expertise and infrastructure necessary to participate as a site in the ATN. Our core staffing plans will allow us to continue effective recruitment and retention into therapeutic, behavioral and community trials. In addition our experienced staff will continue to be active in the development of new protocols and thus allow us to continue to contribute to the ATN scientific agenda. The ATN research agenda is of particular relevance to public health, as it will significantly contribute to our understanding of HIV in adolescents.

描述（由申请人提供）：洛杉矶儿童医院（CHLA）的使命是“通过整合医疗服务，预防服务，医学教育和研究，以促进儿童和青少年的健康和福祉，以应对我们社区的需求，并在我们的爱情，同情心和人们尊重的人中，以自1980年代初期的范围内的范围内的范围内的型号，重新培养了Chla的范围。”与社区合作建立的研究和培训。通过这些计划，该部门每年为9000多名青年提供医疗保健，心理健康，病例管理，健康教育和药物滥用治疗服务，并参与社区水平的怀孕，艾滋病毒和预防暴力的干预措施。自从青少年试验网络（ATM）成立以来，CHLA已将自己确立为生产性的青少年医学试验单位（ATU），这为ATU的主要任务促进了ATU的主要任务，以招募和保留受试者在临床试验和生产中的高质量数据中的招募和保留。在行为试验领域，CHLA的参与和招聘要比任何其他ATM站点都要大得多。对于社区预防试验（Connect To Protect（R）），CHLA是完成指数访谈并开始简短场地调查的前三个（十五个）站点之一。至于治疗试验，CHLA一直在招聘中排名前三。我们的网站管理的质量反映在我们的半年度现场访问中始终如一的积极评价中。洛杉矶ATU不仅将自己确立为富有成效的ATU，而且通过积极参与委员会和发展新行为方案的发展为ATM做出了贡献。该网站PI一直是该项目五年的ATU主席，并在执行和现场绩效委员会任职。此外，CHLA是启动ATN协议的少数ATU站点之一（ATN 039）。 CHLA目前正在开发另一个原始协议，涉及将手机用作提醒的提醒。以下申请文件表明，洛杉矶儿童医院（CHLA），青少年医学部具有作为ATN现场参加的经验，专业知识和基础设施。我们的核心人员配备计划将使我们能够继续有效地招募和保留治疗，行为和社区试验。此外，我们经验丰富的员工将继续积极参与新协议的制定，从而使我们能够继续为ATN科学议程做出贡献。 ATN研究议程与公共卫生特别相关，因为这将极大地有助于我们对青少年中的艾滋病毒的理解。