HIV Risk Among Homeless Mothers

无家可归母亲的艾滋病毒风险

• 批准号: 7127163
• 负责人: CAROL Louise CATON
• 金额: $ 52.41万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7127163
• 关键词: AIDS; AIDS /HIV diagnosis; Chlamydia trachomatis; HIV infections; Trichomonas vaginalis; behavioral /social science research tag; cervical /vaginal smear; child abuse; clinical research; data collection methodology /evaluation; disease /disorder proneness /risk; domestic violence; drug abuse; focus groups; gonorrhea; high risk behavior /lifestyle; homeless; interview; mental disorders; questionnaires; sex behavior; sexually transmitted diseases; social support network; statistics /biometry; urinalysis; women' s health

DESCRIPTION (provided by applicant): This is an amended application addressing issues raised in the IRQ Summary Statement of 8/12/04. Support is requested for a three-year period to conduct a study of HIV prevalence, STI prevalence, and drug and sexual HIV risk behaviors in a random sample of 800 homeless mothers in New York City. The study's qualitative and quantitative components address the gap in information on HIV risk in this fast rising subgroup of the adult homeless in the United States. Homeless mothers possess many characteristics associated with HIV risk behaviors, including childhood sexual and physical abuse, substance abuse, psychiatric disorder, domestic violence, and poor social support. Although HIV infection is significant among the adult homeless, HIV and STI prevalence has not been studied among homeless mothers. HIV prevalence will be determined with the OraSure HIV test based on oral mucosal samples. STI testing for chlamydia, gonorrhea, and trichomoniasis will be based on urine and vaginal swab samples. The research team will be responsible for pre and post test counseling, test results, and treatment for positive assays. Study aims include examining the relationship between HIV prevalence, STI prevalence, and HIV drug and sexual risk behaviors and homelessness, probing the extent to which risk behaviors are influenced by persistent residential instability. Guided by an integrated ecological framework, the study will investigate the relationship of multiple levels of risk and protective factors, including childhood sexual and physical abuse, mental illness, substance abuse, domestic violence, HIV knowledge and attitudes, and social support, to drug and sexual HIV risk behaviors and chronic homelessness. The study will inform the design of HIV risk behavior preventive interventions appropriate to the life circumstances of homeless mothers.

描述（由申请人提供）： 这是一个修正的应用程序，解决 2004 年 8 月 12 日的 IRQ 摘要声明中提出的问题。请求提供为期三年的支持，对纽约市 800 名无家可归母亲进行随机抽样，研究艾滋病毒流行率、性传播感染流行率以及吸毒和艾滋病毒性行为风险行为。该研究的定性和定量部分弥补了美国这一快速增长的成年无家可归者群体中艾滋病毒风险信息的空白。无家可归的母亲具有许多与艾滋病毒危险行为相关的特征，包括儿童时期的性虐待和身体虐待、药物滥用、精神障碍、家庭暴力和不良的社会支持。尽管艾滋病毒感染在成年无家可归者中很显着，但尚未对无家可归母亲中的艾滋病毒和性传播感染患病率进行研究。 HIV 患病率将通过基于口腔粘膜样本的 OraSure HIV 检测来确定。衣原体、淋病和滴虫病的性传播感染检测将基于尿液和阴道拭子样本。研究团队将负责测试前后的咨询、测试结果以及阳性检测的治疗。研究目的包括检查艾滋病毒流行率、性传播感染流行率、艾滋病毒药物和性危险行为与无家可归之间的关系，探讨持续居住不稳定对危险行为的影响程度。在综合生态框架的指导下，该研究将调查多层次的风险和保护因素，包括儿童性虐待和身体虐待、精神疾病、药物滥用、家庭暴力、艾滋病毒知识和态度以及社会支持与毒品和艾滋病毒之间的关系。性艾滋病毒危险行为和长期无家可归。该研究将为设计适合无家可归母亲生活环境的艾滋病毒危险行为预防干预措施提供信息。