HIV Risk Among Homeless Mothers

无家可归母亲的艾滋病毒风险

• 批准号: 7005728
• 负责人: CAROL Louise CATON
• 金额: $ 55.42万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7005728
• 关键词: AIDS; AIDS /HIV diagnosis; Chlamydia trachomatis; HIV infections; Trichomonas vaginalis; behavioral /social science research tag; cervical /vaginal smear; child abuse; clinical research; data collection methodology /evaluation; disease /disorder proneness /risk; domestic violence; drug abuse; focus groups; gonorrhea; high risk behavior /lifestyle; homeless; interview; mental disorders; questionnaires; sex behavior; sexually transmitted diseases; social support network; statistics /biometry; urinalysis; women' s health

DESCRIPTION (provided by applicant): This is an amended application addressing issues raised in the IRQ Summary Statement of 8/12/04. Support is requested for a three-year period to conduct a study of HIV prevalence, STI prevalence, and drug and sexual HIV risk behaviors in a random sample of 800 homeless mothers in New York City. The study's qualitative and quantitative components address the gap in information on HIV risk in this fast rising subgroup of the adult homeless in the United States. Homeless mothers possess many characteristics associated with HIV risk behaviors, including childhood sexual and physical abuse, substance abuse, psychiatric disorder, domestic violence, and poor social support. Although HIV infection is significant among the adult homeless, HIV and STI prevalence has not been studied among homeless mothers. HIV prevalence will be determined with the OraSure HIV test based on oral mucosal samples. STI testing for chlamydia, gonorrhea, and trichomoniasis will be based on urine and vaginal swab samples. The research team will be responsible for pre and post test counseling, test results, and treatment for positive assays. Study aims include examining the relationship between HIV prevalence, STI prevalence, and HIV drug and sexual risk behaviors and homelessness, probing the extent to which risk behaviors are influenced by persistent residential instability. Guided by an integrated ecological framework, the study will investigate the relationship of multiple levels of risk and protective factors, including childhood sexual and physical abuse, mental illness, substance abuse, domestic violence, HIV knowledge and attitudes, and social support, to drug and sexual HIV risk behaviors and chronic homelessness. The study will inform the design of HIV risk behavior preventive interventions appropriate to the life circumstances of homeless mothers.

描述（由申请人提供）： 这是一个修订的申请，涉及8/12/04的IRQ摘要声明中提出的问题。在纽约市的800个无家可归的母亲的随机样本中，要求对三年进行三年的支持，以进行三年的研究研究。该研究的定性和定量成分涵盖了美国成人无家可归者的快速上升亚组中有关艾滋病毒风险的信息的差距。无家可归的母亲具有与艾滋病毒风险行为相关的许多特征，包括儿童期性和身体虐待，滥用药物，精神疾病，家庭暴力和社会支持不佳。尽管在成年无家可归者中，艾滋病毒感染很重要，但尚未在无家可归的母亲中研究艾滋病毒和性传播感染率。 HIV患病率将通过基于口服粘膜样本的ORASURE HIV检验确定。对衣原体，淋病和毛滴虫病的STI测试将基于尿液和阴道拭子样品。研究小组将负责测试前后的咨询，测试结果和阳性测定的治疗。研究目的包括检查HIV患病率，性病患病率与艾滋病毒药物与性风险行为和无家可归的关系之间的关系，探讨风险行为受持续的住宅不稳定影响的程度。在综合生态框架的指导下，该研究将研究多种级别的风险和保护因素的关系，包括儿童性和身体虐待，精神疾病，滥用药物，家庭暴力，艾滋病毒知识和态度以及社会支持与毒品和毒品和毒品的关系性艾滋病毒的风险行为和慢性无家可归。该研究将为适合无家可归母亲的生活环境的艾滋病毒风险行为预防干预措施的设计提供信息。