CORE--BIOSTATISTICS

核心--生物统计学

• 批准号: 7142536
• 负责人: Robert C Young
• 金额: $ 24.32万
• 依托单位: FOX CHASE CANCER CENTER
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-10 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7142536
• 关键词: biomedical facility; neoplasm /cancer; statistical service /center; statistics /biometry

The Biostatistics Facility is a shared institutional resource for biostatistical collaboration and related methodological research. It is recognized as an important aspect of the research infrastructure at the Fox Chase Cancer Center (FCCC). The Facility serves as a focal point from which the Center's investigators may draw statistical expertise for planning, management, and analysis of their studies. This effort spans all three FCCC Divisions and 10 Research Programs. Between January 2000 and June 2004, Facility biostatisticians were involved in the publication of 139 papers and in the design of 261 in-house clinical protocols. During the current funding cycle, this Core has actively served the needs of 69 investigators with peer-reviewed funding on statistical issues concerning their research projects. The Facility was rated "Outstanding" at the last CCSG review. In 2003 the Facility logged 5,464 consulting hours with 91% in support of investigators with peer-reviewed funding. The specific aims of the Biostatistics Facility are: (1) Coordinate and manage statistical activities in the Cancer Center to ensure that every investigator has ready access to statistical consultation and support. (2) Provide statistical expertise in the design of experiments and studies, including research proposal development, sample size determination, randomization procedures, and plans for interim reviews and final analysis. (3) Provide statistical analysis for Cancer Center projects using appropriate statistical and computing methodologies, assist in the interpretation and presentation of results. (4) Provide statistical components for manuscripts. (5) Review, in conjunction with the Scientific Review Committee, the integrity and statistical soundness of all studies involving human subjects. (6) Interact and collaborate with the Population Studies Facility to ensure the retrieval of relevant and valid data. (7) Interact and collaborate with the Protocol Office in the development of protocols and the monitoring and reporting of clinical data. (8) Maintain a library of up-to-date software for statistical analysis. (9) When necessary, develop specialized methods that are clearly and closely related to the support of specific Cancer Center projects.

生物统计设施是生物统计合作和研究的共享机构资源 相关方法论研究。它被认为是研究的一个重要方面 福克斯蔡斯癌症中心 (FCCC) 的基础设施。该设施是一个焦点 中心的调查人员可以从中汲取规划、管理、 并对他们的研究进行分析。这项工作涵盖所有三个 FCCC 部门和 10 个研究部门 节目。 2000 年 1 月至 2004 年 6 月期间，该机构的生物统计学家参与了 发表了 139 篇论文并设计了 261 项内部临床方案。期间 在当前的资助周期中，该核心已积极满足 69 名经过同行评审的研究人员的需求 为其研究项目的统计问题提供资金。该设施是 在上次 CCSG 评审中被评为“优秀”。 2003 年，该机构记录了 5,464 次咨询 91% 的人通过同行评审的资金支持研究人员。 生物统计设施的具体目标是： (1) 协调和管理统计 癌症中心的活动，以确保每个研究人员都能随时获得统计数据 咨询和支持。 (2) 提供实验设计方面的统计专业知识 研究，包括研究提案制定、样本量确定、随机化 中期审查和最终分析的程序和计划。 (3) 提供统计分析 癌症中心项目使用适当的统计和计算方法，协助 结果的解释和呈现。 (4) 提供稿件的统计成分。 (5) 会同科学审查委员会审查完整性和统计性 所有涉及人类受试者的研究的健全性。 (6) 与企业的互动与协作 人口研究设施确保检索相关且有效的数据。 (7) 互动与 与礼宾办公室合作制定协议以及监测和 临床数据报告。 (8) 维护用于统计分析的最新软件库。 (9) 必要时，制定与项目明确且密切相关的专门方法 支持特定癌症中心项目。