Biostatistics Core

生物统计学核心

• 批准号: 7102341
• 负责人: Susan LeRoy Stewart
• 金额: $ 4.47万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7102341
• 关键词: Asian Americans; biomedical facility; cancer prevention; clinical research; data collection methodology /evaluation; data quality /integrity; experimental designs; health disparity; health services research tag; health surveys; hepatitis B; human data; liver neoplasms; statistical service /center; statistics /biometry; virus related neoplasm /cancer

The purpose of the Biostatistics Core is to oversee the statistical aspects of the program project entitled Liver Cancer Control Interventions for Asian Americans, whose long-term objective is to reduce cancer-related health disparities. In particular, the Biostatistics Core will work with the individual projects and the Methodology Core to ensure that 1) the study design, survey development, and data collection enable valid tests of intervention effects and other hypotheses of interest; and 2) statistical analyses are designed, carried out, and reported correctly. Central oversight of statistical functions will enable consistency across projects of study design, survey measures, and analytic methods where appropriate with an economy of effort. In addition, uniform data quality and consistency of measures will facilitate cross-project comparisons and analyses. Specifically, the aims of the Biostatistics Core are to do the following: 1) Work with projects to ensure appropriateness of study designs. 2) Assist projects and the Methodology Core with analytic aspects of survey development. In particular, (a) review survey logic and coding of items, and (b) assess the validity and reliability of survey measures. 3) Work with projects and the Methodology Core to develop consistent standards and procedures for data collection. 4) Provide oversight of statistical analysis activities. In particular, (a) work with projects to ensure that project-specific analyses are designed and performed correctly, and (b) work with the Methodology Core to develop and carry out analyses of cross-project data. 5) Work with authors of manuscripts and reports to ensure accurate reporting of analytic methods and results. The Biostatistics Core will ensure that the statistical aspects of the program project are treated appropriately. In addition, the Core will assure consistency in study design, variables and coding, data quality, analytic methods, and reporting. This consistency will facilitate project-specific analyses and enhance the feasibility of cross-project comparisons, thereby contributing to the overall efficiency and economy of this program project that addresses an important public health concern.

生物统计核心的目的是监督题为“肝脏”的计划项目的统计方面 亚裔美国人的癌症控制干预措施，其长期目标是减少与癌症相关的 健康差异。特别是，生物统计核心将与各个项目和 方法核心确保 1) 研究设计、调查开发和数据收集能够有效 干预效果和其他感兴趣的假设的检验； 2) 设计并进行统计分析 出来，并正确报告。对统计职能的集中监督将实现项目之间的一致性 在适当的情况下，以经济的方式制定研究设计、调查措施和分析方法。在 此外，统一的数据质量和衡量标准的一致性将有助于跨项目比较和 分析。具体来说，生物统计核心的目标是： 1) 与项目合作， 确保研究设计的适当性。 2) 在分析方面协助项目和方法核心 的调查发展。特别是，(a) 审查调查逻辑和项目编码，以及 (b) 评估有效性 和调查措施的可靠性。 3) 与项目和方法论核心合作以开发一致的 数据收集的标准和程序。 4) 监督统计分析活动。在 特别是，(a) 与项目合作，确保设计和执行针对具体项目的分析 正确地，以及 (b) 与方法核心合作开发和进行跨项目数据的分析。 5) 与稿件和报告的作者合作，确保分析方法和报告的准确报告 结果。 生物统计核心将确保该计划项目的统计方面得到适当处理。 此外，核心将确保研究设计、变量和编码、数据质量、分析的一致性 方法和报告。这种一致性将有助于针对具体项目的分析并增强可行性 跨项目比较，从而有助于该计划的整体效率和经济性 解决重要公共卫生问题的项目。