Wireless Monitoring/Reward System for Asthma Inhaler Use

哮喘吸入器使用无线监控/奖励系统

• 批准号: 6884133
• 负责人: Marc Cohen
• 金额: $ 9.6万
• 依托单位: SIXTYSEVEN KILOHERTZ, INC.
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-12 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6884133
• 关键词: adolescence (12-20); asthma; behavior modification; behavioral /social science research tag; biomedical equipment development; computer program /software; computer system design /evaluation; inhalation drug administration; monitoring device; nursing research; portable biomedical equipment; reinforcer; respiratory disorder chemotherapy; telemetry; therapy compliance

DESCRIPTION (provided by the applicant): We theorize that an electronic medication monitor (EMM) attached to a dry powder inhaler (DPI) that communicates wirelessly with a device that provides desirable rewards for appropriate use, can improve the adherence of adolescents to inhaled steroids prescribed for asthma. The objective of the proposed Phase 1 SBIR project is to test the feasibility of this approach. We propose a research plan with the following specific aims: 1. Demonstrate the technical feasibility of an EMM with wireless communication capability by building a proof-of-concept inhaler monitor for the Advair Diskus DPI, 2. Create software that integrates the wireless inhaler monitor into SixtySeven Kilohertz's previously developed Adolescents' Disease Empowerment and Persistence Technology (ADEPT) for Asthma System, 3. Outline an approach to using Contingency Management (CM) theory in ADEPT to reinforce medication adherence. Asthma is the leading serious chronic disease of childhood and its treatment requires proper adherence to prescribed medication. Unfortunately, adolescents' adherence to their prescribed regimen of inhaled steroids is unacceptably low. CM is a theory-based approach that has proven to be effective in changing behavior and improving adherence to prescribed medication. A CM based adherence intervention with adolescents can be successful without needing to answer the difficult question of why their adherence is poor. This project is significant because: 1. It proposes a unique intervention to a serious medical problem that has been frequently studied but for which few systematic solutions have been proposed and tested, 2. It represents an approach to improving adherence that is applicable to a number of chronic diseases of childhood, 3. It is directed at issues of recognized importance in nursing research. The proof-of-concept inhaler monitor to be developed will: 1. Record each actuation of the inhaler with a time and date stamp, 2. Sense that the device is placed near the face during inhalation, 3. Detect multiple dosing and dumping, and 4. Wirelessly transmit data to a recording device, which is capable of sending this data to a server database over the cellular telephone network. This technology has commercial value to healthcare payers and pharmaceutical companies, both of which have financial interests in improving medication adherence.

描述（由申请人提供）：我们推测，连接到干粉吸入器（DPI）的电子药物监测器（EMM）与设备进行无线通信，为正确使用提供理想的奖励，可以提高青少年对吸入类固醇的依从性治疗哮喘。拟议第一阶段 SBIR 项目的目标是测试这种方法的可行性。我们提出了一项具有以下具体目标的研究计划： 1. 通过为 Advair Diskus DPI 构建概念验证吸入器监测器，展示具有无线通信功能的 EMM 的技术可行性，2. 创建集成无线吸入器监测器的软件深入了解 SixtySeven Kilohertz 先前开发的用于哮喘系统的青少年疾病赋权和持久技术 (ADEPT)，3. 概述使用应急管理的方法ADEPT 中的 (CM) 理论旨在加强药物依从性。 哮喘是儿童时期主要的严重慢性疾病，其治疗需要正确遵守处方药物。不幸的是，青少年对吸入类固醇处方治疗的依从性低得令人无法接受。 CM 是一种基于理论的方法，已被证明可以有效改变行为并提高对处方药物的依从性。对青少年进行基于 CM 的依从性干预可以取得成功，而无需回答为什么他们的依从性较差这一难题。 该项目意义重大，因为： 1. 它针对一个严重的医学问题提出了一种独特的干预措施，该问题已被经常研究，但很少提出和测试系统的解决方案， 2. 它代表了一种提高依从性的方法，适用于许多患者3. 它针对护理研究中公认的重要问题。 待开发的概念验证吸入器监测器将： 1. 记录吸入器的每次启动，并附上时间和日期戳， 2. 感知吸入过程中设备是否放置在面部附近， 3. 检测多次给​​药和倾倒， 4.将数据无线传输至记录设备，该记录设备能够通过蜂窝电话网络将该数据发送至服务器数据库。 这项技术对医疗保健支付者和制药公司具有商业价值，这两者都在提高药物依从性方面拥有经济利益。